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   577.1
   Г 93

    Gubsky, Yuriy I..
    Biological chemistry : [textbook for students of medical and pharmaceutical faculties of higher educational establishments of Ukraine] / Yu. Gubsky. - 2nd ed. - Vinnytsia : Nova Knyha, 2018. - 487 p. : il. - На англ. мові. - List references: p. 487. - ISBN 978-966-382-697-4 : 220.00 грн, 320.00 грн
Переклад назви: Біологічна хімія: підручник / Ю. Губський

ДРНТІ	76.03.31
УДК	577.1+612.015](075.8)

Рубрики: БИОХИМИЯ(англ)--підручник(англ)

МЕДИЦИНА

Кл.слова (ненормовані):
підручники(англ)
Анотація: Підручник з біологічної хімії складається з 30 розділів і містить текстові матеріали та велику кількість ілюстрацій, у тому числі хімічні формули, реакції та їх рівняння, рисунки складених внутрішньоклітинних перетворень біомолекул і метаболічні “схеми”. Підручник призначений для студентів медичних та фармацевтичних факультетів вищих навчальних закладів України.CONTENTS PREFACE ................. 10 Part 1. BIOMOLECULES. CELLS. METABOLISM Chapter 1. BIOCHEMISTRY: BIOMOLECULES, METABOLISM.... 13 1.1. Biochemistry as fundamental biomedical science........ 13 1.2. Biomolecules - major classes, representatives....... 14 Chapter 2. PROTEINS. AMINO ACIDS. PEPTIDES........ 19 2.1. Amino acids: structure, properties........... 19 2.2. Peptide bonds, polypeptides............ 24 2.3. Proteins. Levels of protein structure.........28 Chapter 3. NUCLEIC ACIDS. NUCLEOTIDES. DNA. RNA ....... .36 3.1. Nucleic acids and the flow of genetic information .......36 3.2. Nucleotides: structure, biological functions......... 37 3.3. Nucleic acids as polynucleotides: DNA, RNA ........42 Chapter 4. CARBOHYDRATES. SUGARS AND THEIR DERIVATIVES...46 4.1. Monosaccharides. Hexoses. Pentoses. Amino sugars ....... 47 4.2. Oligosaccharides. Homopolysaccharides ........49 4.3. Heteropolysaccharides. Glycoproteins .......... 53 Chapter 5. LIPIDS. FATTY ACIDS. BIOMEMBRANES ........ 57 5.1. General characteristics of lipids. Biological functions ....... 57 5.2. Fatty acids: structure and properties ........58 5.3. Structure and properties of special classes of lipids ..... 61 5.4. Steroids: cholesterol, bile acids, steroid hormones ... .. 67 Chapter 6. CELLS. METABOLISM: GENERAL ASPECTS ...... 71 6.1. Metabolism: overall conception, metabolic pathways ....... 71 6.2. Cells. Compartmentalization of metabolic pathways..... 72 Part 2. ENZYMES. GENERAL METABOLIC PATHWAYS Chapter 7. METABOLISM. ENZYMATIC REACTIONS ........ 777.1. Metabolism: general conceptions, metabolic pathways...... 77 7.2. Enzymes as the principal molecular devices of metabolism .....80 7.3. Enzyme nomenclature and classification........84 7.4. Molecular mechanisms of enzyme catalysis ........ 91 Chapter 8. COENZYMES. CONTROL OF ENZYMATIC REACTIONS ..... .94 8.1. Coenzymes: classification, structure. Vitamins as coenzyme precursors ... .94 8.2. Kinetics of enzyme catalysis. Michaelis - Menten theory....99 8.3. Inhibition of enzymes. Kinds of inhibitors ..... 103 8.4. Enzymic catalysis regulatory mechanisms ......... 107 Chapter 9. BIOENERGETICS-1. CATABOLIC PATHWAYS.TRICARBOXYLIC ACID CYCLE................ 114 9.1. Bioenergetics. ATP and other high-energy compounds ..... 114 9.2. Overview of catabolic pathway steps.......... 116 9.3. Tricarboxylic acid cycle: overview .......... 117 9.4. Tricarboxylic acid cycle: reactions and enzymes ....... 118 Chapter 10. BIOENERGETICS-2. MITOCHONDRIAL ELECTRON TRANSPORT. OXIDATIVE PHOSPHORYLATION ........... 124 10.1. General notions of free energy transfer in biochemical systems ... 124 10.2. Electron transport chain in mitochondria......... 126 10.3. Oxidative phosphorylation. ATP synthase ........ 131 Part 3. METABOLISM OF MAJOR CLASSES OF BIOMOLECULES Chapter 11. CARBOHYDRATE METABOLISM-1. PATHWAYS OF GLUCOSE OXIDATION ................ 137 11.1. Major routes of carbohydrate metabolism......... 137 11.2. Aerobic and anaerobic oxidation of glucose. Glycolysis. ...... 159 11.3. Enzymatic reactions of glycolysis. Regulation of glycolysis .... 140 11.4. Aerobic oxidation of glucose. Oxidative decarboxylation of pyruvate.. 149 11.5. Pentose phosphate pathway .......... 150 Chapter 12. CARBOHYDRATE METABOLISM-2. GLYCOGEN METABOLISM. GLUCONEOGENESIS............ 156 12.1. Glycogen metabolism. Glycogen-storage diseases ..... 156 12.2. Gluconeogenesis: reactions, regulation........ 167 12.3. Regulation of carbohydrate metabolism ....... 172 12.4. Control of blood plasma glucose. Diabetes mellitus....... 174 Chapter 13. LIPID METABOLISM-1. TRIACYLGLYCEROL CATABOLISM. OXIDATION OF FATTY ACIDS. KETOGENESIS ....... 177 13.1. Lipids: general characteristics, biological functions ....... 177 13.2. Fat metabolism: overview, lipolysis ........ 179 13.3. Degradation of fatty acids (rj-oxidation)....... 182 13.4. Ketone bodies. Ketogenesis in diabetes mellitus ...... 188 Chapter 14. LIPID METABOLISM-2. LIPOGENESIS. CHOLESTEROL METABOLISM. LIPID METABOLISM PATHOLOGY ...... 193 14.1. Biosynthesis of fatty acids: reactions, enzymes ....... 193 14.2. Biosynthesis of acylglycerols: triglycerides, phosphoglycerides.... 197 14.3. Sphingolipids: representatives, metabolism ....... 201 14.4. Cholesterol synthesis and biotransformation. Atherosclerosis ....207 Chapter 15. AMINO ACID METABOLISM-1. AMINO ACID DEGRADATION: DEAMINATION, TRANSAMINATION, DECARBOXYLATION. UREA CYCLE ... 213 15.1. Protein turnover. Principal pathways of amino acid metabolism ... 213 15.2. Transamination of amino acids: reactions, enzymes....... 216 15.3. Deamination of amino acids: reactions, enzymes......220 15.4. Decarboxylation of amino acids: reactions, biological significance.... 221 15.5. Amino nitrogen metabolism. Urea cycle: reactions, enzymes... 223 Chapter 16. AMINO ACID METABOLISM-2. AMINO ACID SPECIALIZED METABOLIC PATHWAYS. PORPHYRIN METABOLISM ...... .228 16.1. General pathways of amino acids carbon skeleton degradation ...228 16.2. Specialized pathways of individual amino acid metabolism ... 231 16.3. Amino acids as precursors of biologically important compounds ..242 16.4. Diseases associated with abnormal amino acid metabolism...244 16.5. Biosynthesis and catabolism of porphyrins. Gout.....245 Chapter 17. METABOLISM OF PURINE AND PYRIMIDINE NUCLEOTIDES. PURINE DEGRADATION. GOUT ........ 255 17.1. Nucleotides: structure, biochemical functions ........ 255 17.2. Biosynthesis of purine nucleotides ........ 257 17.3. Biosynthesis of pyrimidine nucleotides ........263 17.4. Catabolism of purine and pyrimidine nucleotides. Gout ......265 Part 4.FUNDAMENTALS OF MOLECULAR BIOLOGY AND GENETICS Chapter 18. GENE, GENOME. DNA REPLICATION ......270 18.1. Gene, genome. DNA, RNA: structure, properties...... .270 18.2. Telomeres. Telomerase ............ 281 18.3. DNA technologies............. 284 Chapter 19. mRNA TRANSCRIPTION. RIBOSOMAL TRANSLATION.....288 19.1. mRNA. Transcription: enzymes, mechanisms ......288 19.2. Genetic code. Translation in ribosomes........ 291 19.3. Ribosomal molecular machinery ..........293 Part 5. METABOLIC CONTROL. HORMONES AND VITAMINS Chapter 20. HORMONES-1. BIOCHEMICAL AND CELLULAR MECHANISMS OF HORMONAL REGULATION .......... 301 20.1. Hormones: general definitions......... 301 20.2. Basic principles of hormone effects ..........303 Chapter 21. HORMONES-2. HORMONES OF PEPTIDE AND PROTEIN NATURE... 308 21.1. Peptide and protein hormones of hypothalamus and hypophysis. ....308 21.2. Protein hormones of pancreatic gland......... 321 Chapter 22. HORMONES-3. AMINO ACID DERIVED HORMONES: CATECHOLAMINES, THYREOIDS. LIPOPHILIC HORMONES .... 327 22.1. Catecholamines and other biogenic amines ....... 327 22.2. Thyroid hormones: representatives, pathology ....... 331 22.3. Steroid hormones: representatives, effects, pathology .... 335 22.4. Hormonal regulation of calcium homeostasis. . ..... 342 22.5. Eicosanoids. Biomedical and pharmacological aspects ....346 Chapter 23. BIOCHEMISTRY OF NUTRITION-1. VITAMINS AS ESSENTIAL COMPONENTS OF HUMAN DIET. WATER-SOLUBLE VITAMINS. ... .350 23.1. Biochemistry of nutrition. Components of human diet ....350 23.2. Vitamins: basic definitions, classes of vitamins ....... 352 23.3. Water-soluble vitamins. Vitamins as coenzymes: structure, biochemical properties............ 353 Chapter 24. BIOCHEMISTRY OF NUTRITION-2. VITAMIN C. LIPID-SOLUBLE VITAMINS AS BIOREGULATORS AND ANTIOXYDANTS .... 367 24.1. Vitamin C (ascorbic acid).......... 367 24.2. Vitamin A (retinol): structure, biochemical functions......370 24.3. Vitamin D (calciferol) as calcium and phosphorous homeostasis regulator... 373 24.4. Vitamin E (tocopherol) as principal antioxidant in human body... 375 24.5. Vitamin K: structure of vitamers. Role in blood clotting.... 377 Part 6. BIOCHEMISTRY OF SPECIALIZED TISSUES AND PHYSIOLOGICAL FUNCTIONS Chapter 25. BIOCHEMISTRY OF BLOOD. HEMOSTASIS. COAGULATION CASCADE SYSTEM ............ .380 25.1. Blood: composition, biochemical functions........380 25.2. Hemoglobin: transport of oxygen. Hemoglobinopathies ......382 25.3. Hemostasis: blood clotting, fibrinolysis. ......... .389 Chapter 26. BIOCHEMISTRY OF SPECIALIZED CELLS AND PHYSIOLOGICAL FUNCTIONS. BIOCHEMISTRY OF LIVER. METABOLISM OF XENOBIOTICS. . . . .398 26.1. Liver: survey of major biochemical functions ......398 26.2. Liver: metabolism of heme and bile pigments. Bilirubin transformation. Icterus......... .403 26.3. Liver detoxification function. Biotransformation of xenobiotics and endogenous waste products .........408 Chapter 27. BIOCHEMISTRY OF TOOTH AND SALIVA ..... .415 27.1. Anatomy and physiology of human teeth ......... 415 27.2. Biochemical composition and molecular organization of dental tissues... 417 27.3. Tooth enamel: properties, biochemical composition ...... 417 27.4. Dentin: structure, biochemistry. Periodontum. Cementum ....420 27.5. Tooth pulp: physiology, metabolism ..........426 27.6. Tooth pathology. Caries: biochemical aspects ........ 427 27.7. Biochemical components and functions of saliva......428 Chapter 28. BIOCHEMISTRY OF MUSCLES. MOLECULAR PHYSIOLOGY OF MUSCLE CONTRACTION. .......... .430 28.1. Muscle tissue: general characteristics of functions, structure and biochemistry .............430 28.2. Sliding filament model of muscle contraction. Role of calcium in muscle contraction control .........440 28.3. Regulation of muscle contraction. Role of calcium in muscle contraction control............444 Chapter 29. BIOCHEMISTRY AND MOLECULAR PATHOLOGY OF CONNECTIVE TISSUE ...........446 29.1. Connective tissue: cells and biomolecules ........446 29.2. Structural and adhesive proteins of connective tissue. Structural proteins of extracellular matrix ........450 29.3. Biochemistry of extracellular matrix. Glycosaminoglycans and proteoglycans of connective tissue ....... 457 29.4. Molecular pathology of connective tissue ........462 Chapter 30. BIOCHEMISTRY OF SPECIALIZED CELLS AND PHYSIOLOGICAL FUNCTIONS. BIOCHEMISTRY OF NERVE TISSUE AND NEUROTRANSMITTERS... 466 30.1. Nerve tissue: general characteristics of structure and functions ..466 30.2. Peculiarities of brain biochemical composition and metabolism...469 30.3. Neurotransmitters: classification, receptors, representatives ....470 30.4. Drugs, neurotransmitters and synapses.......483 LIST OF REFERENCES ...........487
Дод.точки доступу:
Губський, Юрій Іванович

Примірників всього: 188
ЧЗ (1), Наук.Аб. (3), Уч.Аб. (184)
Вільні: ЧЗ (1), Наук.Аб. (3), Уч.Аб. (184)

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   577.1
   Г 68

    Hordiienko, L. P.
    Biological chemistry : сollection of test tasks : textbook / L. P. Hordiienko, M. V. Bilets, K. S. Neporada ; Ministry of public health of Ukraine, Ukrainian medical stomatological academy = Біологічна хімія : збірник тестових завдань : навчальний посібник / Л. П. Гордієнко, М. В. Білець, К. С. Непорада ; МОЗ України, УМСА. - Полтава/Poltava : Сімон, 2018 (Гаража М. Ф.). - 147 p. - На англ. мові. - ISBN 978-966-2989-79-6 : 025.00 грн
Обкл.: без авт., на англ. мові

УДК

577.1(075.8)

Рубрики: БИОХИМИЯ(АНГЛ)--навчальний посібник(англ)

Кл.слова (ненормовані):
навчальні посібники(англ)
Анотація: CONTENTS Module ІІ .................................... 7 1. Control of initial level of knowledge. The subject and tasks of biochemistry. The aim and methods of biochemical research, its clinical and diagnostic value .............. 7 2.Analysis of structure, physical and chemical properties of protein enzymes .......... 9 3. Measurement of enzymic activity. Units of catalytic activity of enzymes. Analysis of enzymic processes by the reaction type of main classes of enzymes ............... 11 4.Analysis of the mechanism of enzymic action and kinetics of enzymic catalysis ....... 13 5.Analysis of regulation of enzymic processes ..................... 16 6.Medical enzymology ............................... 18 7. Analysis of the role of cofactors and coenzyme vitamins (В2, РР, В6) in the catalytic activity of enzymes ..................................... 22 8. Analysis of the role of cofactors and coenzyme vitamins (В3, Вс, В1, В12, Н, lipoic acid) in the catalytic activity of enzymes ............................. 23 9. Basic concepts of metabolism. Common catabolic pathways of proteins, carbohydrates and lipids .................................... 26 10.Metabolism of substances and energy. Analysis of the tricarboxylic acid cycle ....... 28 11.Bioenergetics processes: biological oxidation, oxidative phosphorylation ......... 29 12. Chemiosmotic theory of oxidative phosphorylation. Inhibitors and uncouplers of oxidative phosphorylation .................................. 31 13.Analysis of glycolysis – anaerobic oxidation of carbohydrates ............ 33 14.Analysis of aerobic oxidation of glucose ...................... 36 15.Alternate pathways of monosaccharide metabolism. Metabolism of fructose and galactose ... 38 16.Analysis of catabolism and biosynthesis of glycogen. Regulation of glycogen metabolism ... 40 17.Gluconeogenesis .............................. 42 18.Analysis of mechanisms of metabolic and hormone regulation of carbohydrate metabolism . 44 19. Analysis of catabolism and biosynthesis of triacylglycerols. Determination of molecular mechanisms of regulation of lipolysis ........................ 46 20.Transport forms of lipids ............................. 48 21.β-oxidation of fatty acids. Analysis of metabolism of fatty acids and ketone bodies ...... 50 22.Biosynthesis of fatty acids ........................... 52 23.Metabolism of complex lipids ........................... 54 24. Biosynthesis and biotransformation of cholesterol. Analysis of disorders of lipid metabolism: steatorrhea, atherosclerosis, obesity ........................ 57 25.Analysis of amino acid metabolism (transamination, deamination, decarboxylation) .... 59 5 26.Biosynthesis of glutathione and creatine ....................... 61 27.Analysis of ammonia detoxication and urea biosynthesis .............. 63 28. Analysis of intermediate products of porphyrin biosynthesis and their accumulation at porphyrias .................................. 66 Module ІІІ ................................... 68 1.Structure and functions of nucleic acids....................... 68 2. Study of biosynthesis and catabolism of purine and pyrimidine nucleotides. Analysis of the end products of their metabolism ............................. 71 3.DNA replication and RNA transcription ...................... 74 4. Biosynthesis of proteins on ribosomes. Initiation, elongation and termination in the synthesis of polypeptide chain. Inhibitory action of antibiotics .................... 76 5.Regulation of gene expression ......................... 79 6.Analysis of mutation mechanisms, DNA reparation. Principles of synthesis of recombinat DNA, transgenic proteins ................................. 81 7. Study of molecular cellular mechanisms of action of peptide and protein hormones on target cells. Hormones of hypothalamus and hypophysis ................... 83 8. Study of molecular cellular mechanisms of action of steroid hormones on target cells. Steroid hormones ................................... 86 9.Study of role of thyroid hormones and biogenic amines in regulation of metabolic processes . 89 10.Hormones of pancreas. Hormones of the digestive tract ................ 91 11.Hormonal regulation of calcium homeostasis ..................... 93 12.Physiologically active eicosanoids ....................... 96 13.Study of digestion of nutrients: proteins, carbohydrates in the digestive tract ....... 98 14.Study of digestion of nutrients: lipids in the digestive tract ............. 100 15. Study of functional role of fat-soluble vitamins in the metabolism and realization of cell functions .................................. 102 16. Study of blood plasma proteins: proteins of acute phase of inflammation, own enzymes and indicator enzymes ................................ 105 17. Study of acid-base state of blood and respiratory function of erythrocytes. Pathological forms of hemoglobins ................................. 107 18. Study of nitrogen balance and non-protein nitrogen containing components of blood – end products of heme catabolism ........................... 110 19.Biochemical patterns of realization of immune processes. Immunodeficiency states ... 113 20.Biochemistry of liver. Pathobiochemistry of jaundices ................ 115 6 21. Study of processes of biotransformation of xenobiotics and endogeneous toxins. Microsomal oxidation, cytochrome P-450 .......................... 119 22.Study of normal components of urine. Study of pathological components of urine ...... 121 23.Biochemistry of muscle tissue ......................... 125 24.Biochemistry of connective tissue ......................... 127 25.Biochemistry of bone tissue. Risk factors of osteoporosis ............... 130 26.Biochemistry of nervous tissue .......................... 132 TESTS «BIOCHEMISTRY OF ORGANS OF ORAL CAVITY» ........... 135 Biochemistry of the dental tissue .......................... 135 Biochemistry of saliva ............................... 137 Biochemical mechanisms of the main stomatological diseases development ......... 138 ANSWERS TO THE TEST TASKS ........................ 143
Полный текст/внешний ресурс скачать: БД Електронний ресурс. № 277

Дод.точки доступу:
Bilets, M. V.
Білець М. В.
Neporada, K. S.
Непорада К.С.
Гордієнко Л. П.
UMSA (Poltava)

Примірників всього: 2
Наук.Аб. (2)
Вільні: Наук.Аб. (2)

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   577.1
   І-44


    Harper's Illustrated Biochemistry / R. K. Murray, D. A. Bender, K. M. Botham et al. - 28th ed. - New York etc. : McGraw-Hill, Medical, 2009. - x, 693 p. : il. ; 28 cm. - (A LANGE medical book, ISSN 1043-9811). - Co-Autors: p. iii. - На англ. мові. - References: p. 4-5. - Glossary: p. 5. - Index: p. 651-693. - ISBN 978-0-07-162591-3. - ISBN 0-07-162591-7 : 200.00 грн
Переклад назви: Ілюстрована біохімія Харпера

ДРНТІ	31.27
УДК	577.1

Рубрики: БИОХИМИЯ(англ)

Анотація: The biochemistry text that every medical student must own--now in full color! Comprehensive, concise, and up-to-date, Harper's is unrivaled in its ability to clarify the link between biochemistry and the molecular basis of health and disease. The Twenty-Eighth Edition has undergone sweeping changes -- including a conversion to full-color artwork and the substantial revision and updating of every chapter -- all to reflect the latest advances in knowledge and technology and to make the text as up-to-date and clinically relevant as possible. Combining outstanding full-color illustrations with integrated coverage of biochemical diseases and clinical information, Harper's Illustrated Biochemistry offers an organization and clarity not found in any other text on the subject. Striking just the right balance between detail and brevity, Harpers Illustrated Biochemistry is essential for USMLE review and is the single best reference for learning the clinical relevance of a biochemistry topic. NEW to this edition: Full-color presentation, including 600+ illustrations Every chapter opens with a Summary of the Biomedical Importance and concludes with a Summary reviewing the topics covered Two all-new chapters: "Free Radicals and Antioxidant Nutrients" and "Biochemical Case Histories" which offers an extensive presentation of 16 clinical conditions A new appendix containing basic clinical laboratory results and an updated one with a list of important websites and online journals NEW or updated coverage of important topics including the Human Genome Project and computer-aided drug delivery
Дод.точки доступу:
Murray, Robert K.
Bender, David A.
Botham, Kathleen M. (PhD, DSc, Professor of Biochemistry, Department of Comparative Biomedical Sciences, Royal Veterinary College, University of London, London, United Kingdom)
Kennelly, Peter J. (PhD, Professor and Head, Department of Biochemistry, Virginia Tech, Blacksburg, Virginia)
Rodwell, Victor W. (PhD, Professor (Emeritus) of Biochemistry, Purdue University, West Lafayette, Indiana)
Weil, P. Anthony (PhD, Professor, Department of Molecular Physiology & Biophysics, Vanderbilt University, Nashville, Tennessee)

Примірників всього: 1
Наук.Аб. (1)
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   577.1
   Г 93

    Gubsky, Yu.
    Biological chemistry : [textbook for students of medical and pharmazeutical faculties of higher educational establishments of Ukraine] / Yu. Gubsky. - Vinnytsia : Nova Knyha, 2017. - 487 p. : il. - На англ. мові. - List references: p. 487. - ISBN 978-966-382-609-7 : 220.00 грн
Переклад назви: Біологічна хімія: підручник / Ю. Губський

ДРНТІ	76.03.31
УДК	577.1+612.015](075.8)

Рубрики: БИОХИМИЯ(англ)--підручник(англ)

МЕДИЦИНА

Кл.слова (ненормовані):
підручники
Анотація: Підручник з біологічної хімії складається з 30 розділів і містить текстові матеріали та велику кількість ілюстрацій, у тому числі хімічні формули, реакції та їх рівняння, рисунки складених внутрішньоклітинних перетворень біомолекул і метаболічні “схеми”. Підручник призначений для студентів медичних та фармацевтичних факультетів вищих навчальних закладів України.
Дод.точки доступу:
Губський Юрій Іванович

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   577.1
   М 25

    Mardashko, O. O.
    Biochemistry : Texts of lectures / O. O. Mardashko, N. Ye. Yasinenko ; ed. O. O. Mardashko. - Odessa : Odessa State Medical University, 2003. - 418 p. : il. - (Medikal Students Library : initiated in 1999 to markthe Centenary of the Odessa State Medical University (1900-2000) / ed. and published V.M. Saporozhan). - На англ. мові. - References : р. 412. - ISBN 966-7733-33-5 : 095.00 грн
Переклад назви: Біохімія: тексти лекцій / О.О. Мардашко, Н.Є. Ясиненко

ДРНТІ	31.27
УДК	577.1(075.8)

Рубрики: Биохимия(англ)--Навчальний посібник(англ)

Кл.слова (ненормовані):
Texts of lecture
Дод.точки доступу:
Yasinenko, N. Ye.
Ясиненко Н. Є.
Mardashko, O. O. \ed.\
Мардашко О. О.

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ЧЗ (2)
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