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   616-092
   П 20


    Pathophysiology : textbook [for students of higher medical educational establishments] / ed. N. V. Krishtal, V. A. Mikhnev ; N. V. Krishtal, V. A. Mikhnev, N. N. Zayko et al. - 2nd ed. correct. - K. : Medicine Publishing, 2018. - 655 p. : il. - На англ. мові. - References: p. 603-637. - Index: p. 638-655. - ISBN 978-617-505-759-9 : 300.00 р.
Переклад назви: Патофізіологія: підручник / за ред. М. В. Кришталя, В. А. Міхньова

УДК

616-092(075.8)

Рубрики: ПАТОФІЗІОЛОГІЯ(англ)--Підручник

Кл.слова (ненормовані):
підручники англійською -- national textbook
Анотація: The textbook is prepared by a team of staff at higher educational institutions and academic research institutions of Ukraine, who are recognized experts in various aspects of pathophysiology that gives reason this basic textbook to be national. It is recommended for English-speaking students of higher medical educational establishments. The textbook can be useful for teachers and physicians of all specialties. Abbreviations........................ 11 Preface........................... 14 Introduction (MD, PhD, DSc, Professor Nikolay N. Zayko).......15 The Subject and Tasks of Pathological Physiology............ 15 Relationship Between Pathological Physiology and Other Medical Sciences, Its Importance for Clinical Disciplines................ 15 Experiment as the Basic Method of Pathological Physiology........ 16 Historical Sketch of the Development of Pathological Physiology (MD, PhD, DSc, Professor Valentin F. Myslitskiy; MD, PhD, DSc, Professor Sergey V. Ziablitsev)...18 Part One GENERAL NOSOLOGY Chapter I. GENERAL THEORY OF DISEASES (MD, PhD, DSc, Professor Nikolay N. Zayko).............. 23 Health............................. 23 Disease............................. 24 Principles of Diseases Classification................. 25 Pathological Reaction, Pathological Process, Pathological Condition......26 Typical Pathological Processes......... 27 Main Periods (Stages) of Disease Development....... 27 Chapter II. ETIOLOGY AND PATHOGENESIS (MD, PhD, DSc, Professor Nikolay N. Zayko)..... 31 Etiology................... 31 Conditions of the Disease Occurrence...... 33 Pathogenesis................. 34 The Cause-and-Effect Relationship......... 35 General and Local.............. 36 Structure and Function............. 36 Nonspecific and Specific............ 36 Adaptation and Compensation.......... 37 Reactivity and its Role in Pathology (MD, PhD, DSc, Professor Liudmila Ya. Danilova) 38 Types of Resistance. Relations with Reactivity..... 39 Chapter III. PATHOGENIC EFFECT OF ENVIRONMENTAL FACTORS ON THE ORGANISM (MD, PhD, Associate Professor Natalia K. Simeonova) 41 Mechanical Trauma............. 41 Thermal Trauma............. 41 Barotrauma.............. 45 Radiation Injury.............. 46 Etiology............. 46 Pathogenesis............ 47 Acute Radiation Disease.......... 53 Chronic Radiation Disease........... 54 Electrotrauma.............. 55 Pathogenic Effect of Space Flight Factors....... 56 Chapter IV. THE ROLE OF HEREDITY, CONSTITUTION AND AGE IN PATHOLOGY (MD, PhD, Associate Professor Natalia K. Simeonova)....... 57 Genetically Determined Diseases........ 57 Classification............. 57 Etiology............. 58 Pathogenesis............ 59 Molecular Genetic (Hereditary) Diseases...... 60 Chromosomal Diseases.......... 65 Hereditary Predisposition........... 66 Genetic Examination of a Patient....... 66 Principles of Prevention and Treatment of Hereditary Diseases 69 Role of The Constitution in Pathology........ 70 Pathological Physiology of Fetal Development (MD, PhD, DSc, Professor Larisa A. Popova)...... 73 Ageing (MD, PhD, DSc, Professor Gennadiy M. Butenko)..... 74 Changes in the Body during Aging....... 77 Ageing and Diseases........... 82 Causes and Mechanisms of Ageing........ 83 The Ways of Influence on Ageing........ 84 Part Two GENERAL PATHOPHYSIOLOGY OF CELLS. TYPICAL METABOLIC DISORDERS Chapter V. PATHOPHYSIOLOGY OF CELL (MD, PhD, DSc, Professor Gennadiy M. Butenko)...... 86 Disturbances of Cells Functions........ 86 Disorders of Metabolic Processes and Environment Interaction... 87 Disturbance of Cell Energy Supply......... 88 Disturbances of Genetic Information Storage and Transfer. 89 Intracellular Synthesis Disorders......... 91 Dissimilation Interruption.......... 92 Cell Damage and Death............ 93 Chapter VI. PATHOLOGY OF ENERGY BALANCE (MD, PhD, DSc, Professor Liudmila Ya. Danilova; MD, PhD, DSc, Professor Nikolay V. Krishtal)..... 95 Chapter VII. PATHOPHYSIOLOGY OF CARBOHYDRATE METABOLISM (MD, PhD, DSc, Professor Liudmila Ya. Danilova; MD, PhD, DSc, Professor Nikolay V. Krishtal).... 98 Carbohydrate Metabolism and its Regulation...... 98 Pathology of the Carbohydrate Metabolism....... 100 Chapter VIII. Pathophysiology OF lipid METABOLISM (MD, PhD, DSc, Professor Nikolay V. Krishtal; MD, PhD, DSc, Professor Liudmila Ya. Danilova)... 105 Malabsorption of Lipids............ 105 Disorders of Lipid Transport and Deposition....... 105 Lipid Infiltration and Lipid Dystrophy...... 107 Disorder of Intermediate Lipid Metabolism...... 107 Disorders of Lipid Metabolism in The Adipose Tissue..... 108 Obesity................ 109 Weight Loss............... 114 Lipidoses.............. 115 Chapter IX. PATHOPHYSIOLOGY OF PROTEIN METABOLISM (MD, PhD, DSc, Professor Larisa A. Popova; MD, PhD, DSc, Professor Victor Ye. Dosenko).... 116 Disorders of Amino Acid Metabolism....... 116 Hereditary Disorders of Metabolism of Certain Amino Acids.. 117 Disorders of Final Stages of Protein Metabolism...... 119 Disorders of Proteins of the Blood....... 120 Disorders of the Nucleic Acids Metabolism...... 120 Chapter X. PATOPHYSIOLOGY OF ACID-BASE HOMEOSTASIS (MD, PhD, DSc, Professor Nikolay V. Krishtal)..... 122 Etiology, Pathogenesis and Forms of Acid-Base Imbalance.... 124 The Relationship between ABH and Mineral Exchange.... 124 Etiology and Classification of Non-Respiratory Acid-Base Imbalance 126 Pathological Effects of Acid-Base Imbalance on the Body.... 127 Mechanisms of Compensation of Acid-Base Imbalance.... 128 Chapter XI. PATOPHYSIOLOGY OF WATER-ELECTROLYTE BALANCE (MD, PhD, DSc, Professor Nikolay V. Krishtal; MD, PhD, DSc, Professor Oleg I. Sukmanskiy).... 132 Types, Causes, and Consequences of Water-Electrolyte Imbalance 136 Electrolyte Imbalance........... 142 The Exchange of Sodium and Its Imbalance....... 142 The Exchange of Potassium and Its Imbalance.... 143 The Exchange of Magnesium and Its Imbalance.... 144 The Exchange of Chlorine and Its Imbalance..... 145 The Exchange of Calcium and Its Imbalance...... 146 The Exchange of Phosphorus and Its Imbalance...... 148 The Osteoporosis............. 149 Chapter XII. PATHOPHYSIOLOGY OF MICROELEMENTS METABOLISM (MD, PhD, DSc, Professor Nikolay V. Krishtal)..... 151 Iron Exchange and Imbalance........... 152 Copper Exchange and Imbalance......... 156 Zinc Exchange and Imbalance........... 159 Manganese Exchange And Imbalance......... 161 Chromium Exchange and Imbalance.......... 162 Vanadium Exchange and Imbalance.......... 163 Molybdenum Exchange and Imbalance........ 165 Selenium Exchange and Imbalance.......... 165 Iodine Exchange And Imbalance......... 169 Fluoride Exchange and Imbalance.......... 171 Chapter XIII. PATHOPHYSIOLOGY OF VITAMINS METABOLISM (MD, PhD, DSc, Professor Nikolay V. Krishtal)..... 173 Classification and General Characteristics of Vitamins in the Human Body 173 Sources of Vitamins and Their Metabolism in the Body.... 177 Main Causes of Vitamin Deficiency Development..... 179 Deficiency of Antineurotic Vitamin В1........ 181 Deficiency of Riboflavin........... 182 Deficiency of Antipellagric Vitamin РР...... 182 Deficiency of Antidermatitic Vitamin В6...... 183 Deficiency of Folic Acid........... 184 Deficiency of Antianemic Vitamin В12...... 185 Deficiency of Antiscorbutic Vitamin C....... 186 Deficiency of Biotin............ 187 Deficiency of Rutin.......... 188 Deficiency of Antixerophthalmic Vitamin A...... 188 Deficiency of Antirachitic Vitamin D........ 188 Deficiency of Vitamin E......... 190 Deficiency of Vitamin F......... 191 Deficiency of Antihemorrhagic Vitamin K..... 192 Hypervitaminoses............. 192 Part Three TYPICAL PATHOLOGICAL PROCESSES Chapter XIV. Pathophysiology of peripheral blood CIRCULATION (MD, PhD, DSc, Professor Yuriy V. Byts; MD, PhD, DSc, Professor Anatoliy V. Kubyshkin).... 194 Arterial Hyperemia........... 196 Venous Hyperemia............. 201 Ischemia............... 202 Stasis.............. 206 Thrombosis............. 206 Embolism............... 209 Chapter XV. microcirculatory disorders (MD, PhD, DSc, Professor Yuriy V. Byts; MD, PhD, DSc, Professor Anatoliy V. Kubyshkin) 213 Intravascular Mechanisms of Microcirculatory Disorders.. 214 Extravascular Mechanisms of Microcirculatory Disorders.. 217 Chapter XVI. INFLAMMATION (MD, PhD, DSc, Professor Nikolay V. Krishtal) 218 Experimental Models of Inflammation......... 219 Etiology of Inflammation........... 220 Pathogenesis of Inflammation.......... 220 Alteration............. 221 The Inflammatory Cells and Mediators........ 225 The Influence of Inflammatory Mediators on the Organism. 233 Vascular Reactions in Inflammation....... 234 Exudation.............. 236 Emigration of the White Blood Cells...... 237 Phagocytosis.............. 242 Proliferation and Regeneration........ 244 Classification............ 249 Chapter XVII. PATHOPHYSIOLOGY OF THE IMMUNITY (MD, PhD, DSc, Professor Vladislav A. Horban; MD, PhD, DSc, Professor Nikolay V. Krishtal) 251 The Main Functions and Structure of the Immune System... 251 Genesis and Function of T- and B-Lymphocytes...... 253 Experimental Models of Hypofunction of the Immune System... 257 Immune Deficiency Diseases......... 257 Immune-Suppressive Diseases........ 263 Disorders of the Systems that Functionally Associated with the Immune System 264 Chapter XVIII. ALLERGY (MD, PhD, DSc, Professor Vladislav A. Horban) 267 Etiology............... 267 Classification of Allergens........ 267 Pathogenesis.............. 269 Immunological Stage of Allergic Reactions and Their Classification 269 The Pathochemical Stage of Allergic Reactions..... 274 Pathophysiological Stage of Allergic Reactions.... 276 Mechanisms of Formation of Allergic Reactions..... 277 Autoallergic Diseases........... 279 False Allergy (Paraallergy, Heteroallergy)..... 281 Prevention of the Allergy. Desensibilization...... 282 Chapter XIX. FEVER (MD, PhD, DSc, Professor Nikolay N. Zayko). 283 Etiology............... 283 Pathogenesis. The Role of the Thermoregulatory Centers in the Fever Development 284 Stages of the Fever............. 288 Types of Temperature Curves........... 289 Difference between Fever and Hyperthermia...... 291 Effect of Fever on Body Organs and Systems..... 292 Significance of Fever for Organism....... 293 Chapter XX. TUMORS (NEOPLASMS) (MD, PhD, DSc, Professor Vladislav A. Horban)..... 295 Experimental Models of Neoplasia......... 295 Features of the Neoplastic Tissue........ 296 Malignancy of Tumors............ 298 Etiology of Tumor............ 299 Pathogenesis of Tumor........... 302 The Tumor Effect on the Organism......... 309 The Role of the Organism in the Neoplastic Process... 310 Chapter XXI. STARVATION (MD, PhD, DSc, Professor Liudmila Ya. Danilova) 313 The Complete Starvation............ 313 Incomplete Starvation........... 318 Partial Starvation........... 319 Chapter XXII. HYPOXIA (MD, PhD, Associate Professor Natalia K. Simeonova) 321 Etiology............... 321 Pathogenesis.............. 322 Compensatory and Adaptive Reactions......... 322 Immediate Compensatory Reactions......... 323 Delayed Compensatory Reactions........ 324 Adaptation............. 326 Pathological Changes During the Hypoxia........ 326 Part Four PATHOPHYSIOLOGY OF ORGANS AND SYSTEMS Chapter XXIII. PATHOPHYSIOLOGY OF THE BLOOD SYSTEM (MD, PhD, Associate Professor Irina I. Pototskaya)... 329 Total Blood Volume Disorders.......... 329 Hemorrhage............. 331 Pathology of the Erythrocytes......... 332 Erythrocytosis............ 334 Anemia.............. 335 The Posthemorrhagic Anemia......... 336 Hemolytic Anemia............. 337 The Dyserythropoietic Anemia.......... 341 Pathological Changes of the Leukocytes...... 347 Disorders of the Leukopoiesis......... 347 Quantitative Changes of the Leukocytes in the Blood.. 347 The Qualitative Changes of the Leukocytes in the Blood.. 351 Hemoblastosis, Leukemia......... 354 Pathology of the Hemostasis........... 358 Hemorrhagic Syndromes........... 359 Thrombotic Syndromes............ 363 Chapter ХХIV. Pathophysiology of cardiovascular disorders CAUSED BY HEART DYSFUNCTION (MD, PhD, DSc, Professor Gennadiy M. Butenko)..... 367 Heart Failure............. 368 Heart Failure Associated with Volume Overload. Mechanisms of Compensation 369 Heart Failure due to Myocardium Damage...... 377 Cardiac Rhythm Disorders........... 383 Chapter XXV. Pathophysiology of cardiovascular disorders CAUSED BY VESSELS DYSFUNCTION (MD, PhD, DSc, Professor Yuriy V. Byts; MD, PhD, DSc, Professor Nikolay V. Krishtal) 390 Pathological Changes in the Vessels of the Compensatory Type. Atherosclerosis 392 Experimental Models of the Atherosclerosis..... 393 Etiology............... 393 Pathogenesis.............. 399 Pathophysiology of Vessels of the Resistance (Muscle) Type. 403 Arterial Hypertension........... 403 Experimental models of the hypertension..... 404 Etiology............... 406 Pathogenesis.............. 407 Pulmonary Hypertension.......... 414 Arterial Hypotension............ 415 Chapter XXVI. PATHOPHYSIOLOGY OF EXTREME STATES (MD, PhD, Associate Professor Larisa P. Zayarnaya)... 417 Shock............... 417 Etiology............... 417 Pathogenesis.............. 418 Specific Features of the Shock Development..... 428 Collapse............... 435 Chapter XXVII. PATHOPHYSIOLOGY OF THE RESPIRATION (MD, PhD, DSc, Professor Vladimir A. Mikhnev)..... 440 Disorders of the Alveolar Ventilation....... 440 Disregulative Ventilative Respiratory Insufficiency.. 441 Obstructive Ventilative Insufficiency....... 446 Restrictive Ventilative Insufficiency....... 448 Disorders of the Respiration in the Pulmonary Obstructive and Restrictive Processes.............. 451 Diffusive Insufficiency of the Lungs........ 451 Decrease of the Total Blood Flow in the Lungs..... 454 Breaking of the Total and Local Ventilation-Perfusion Ratio in the Lungs 454 Impact of the Respiratory Failure on the Body..... 456 Disorders of Non-Respiratory Functions of the Lungs..... 459 Chapter XXVIII. PATHOPHYSIOLOGY OF THE DIGESTIVE SYSTEM (MD, PhD, DSc, Professor Oleg I. Sukmanskiy; MD, PhD, DSc, Professor Vitaliy A. Kostenko)...... 461 Appetite Disorder............ 461 Digestive Disorders in the Oral Cavity...... 463 The Chewing Disorder............ 463 Dental Caries............. 463 Periodontal Pathology........... 465 Disorders of Salivation......... 466 Disorders of Swallowing and Esophageal Motility...... 468 Digestive Disorders in the Stomach....... 469 Disorders of the Stomach Secretion....... 469 Disorders of the Stomach Motility........ 471 Peptic Ulcer.............. 475 Intestinal Digestive Disorders........ 478 Digestive Disorders Connected with Impairment of the Bile and Pancreatic Juice Secretion... 478 Pancreatitis.............. 479 Disorders of the Parietal Digestion...... 481 Disorder of Intestinal Absorption. Malabsorption Syndrome. 483 Intestinal Motility Disorders......... 484 Intestinal Obstruction.......... 485 Intestinal Dysbiosis. Intestinal Autointoxication.... 486 Disorders of Hormone Synthesis in the Digestive System.. 487 Chapter XXIX. PATHOPHYSIOLOGY OF THE LIVER (MD, PhD, Associate Professor Irina I. Pototskaya)... 490 General Characteristics of Pathological Processes in the Liver 490 Hepatic Insufficiency........... 491 Disorders of the Metabolism in Liver........ 493 Hepatic Protective Dysfunctions....... 496 Hepatic Coma.............. 497 Disorders of the Cholopoiesis and Cholekinesis.... 499 Disorders of the Hemodynamics at Deseases of Liver... 506 Chapter XXX. PATHoPHYSIOLOGY OF THE KIDNEYS (MD, PhD, DSc, Professor Nikolay V. Krishtal; MD, PhD, DSc, Professor Anatoliy I. Gozhenko) 508 Disorders of the Renal Functions and Processes.... 508 Disorders of Glomerular Filtration....... 509 Disorders of Tubular Reabsorption and Secretion... 511 Pathogenesis of the Renal Syndromes......... 515 Nephrotic Syndrome........... 517 Acute Renal Failure.......... 518 Chronic Renal Failure........... 520 Tubulointerstitial Syndrome........ 521 Etiology and Pathogenesis of the Main Renal Diseases.... 522 Glomerulonephritis........... 522 Pyelonephritis............ 525 Chapter XXXI. PATHOPHYSIOLOGY OF THE ENDOCRINE SYSTEM (MD, PhD, DSc, Professor Aleksandr G. Reznikov)... 527 Hormones and Their Role in the Body......... 527 Etiology and Pathogenesis of Endocrine Disorders..... 530 Dysfunction of the Hypothalamic-Pituitary System..... 538 Dysfunctions of the Pituitary......... 538 Neuroendocrine Diseases......... 541 Disorders of Other Endocrine Organs......... 542 Dysfunctions of the Thyroid Gland........ 542 Dysfunctions of the Parathyroid Glands...... 546 Dysfunctions of the Adrenal Glands....... 547 Dysfunctions of the Sex Glands........ 550 The Endocrine Dysfunction of the Thymus..... 552 Dysfunctions of the Pineal Body (Epiphysis).... 552 Stress and General Adaptation Syndrome...... 553 Diabetes Mellitus (MD, PhD, DSc, Professor Nikolay V. Krishtal) 554 Type 1 Diabetes Mellitus........... 557 Type 2 Diabetes Mellitus........... 562 Chapter ХХХII. PATHOPHYSIOLOGY OF THE NERVOUS SYSTEM (MD, PhD, DSc, Professor Vladimir A. Mikhnev)..... 566 Etiology and Pathogenesis of the Nervous System Disorders.. 566 Dysfunctions of the Nervous System....... 569 Dysfunctions of the Nerve Cells and Conductors.... 569 Dysfunctions of the Synapses.......... 571 Disorders of the Sensitivity.......... 573 Pain................ 575 Disorders of the Motor Functions of the Nervous System.. 580 The Nervous Trophicity and Dystrophic Process..... 586 Dysfunctions of the Autonomic Nervous System...... 589 Experimental Models of Emotional Reactions and their Disorders 591 Coma (MD, PhD, Associate Professor Larisa P. Zayarnaya).... 595 References............. 603 Index 638
Дод.точки доступу:
Krishtal, Nikolay Vasylovych
Кришталь Микола Васильович
Mikhnev, Volodymyr Anatoliyovych
Міхньов Володимир Анатолійович
Zaykо, Nikolay Nykyforovych
Зайко Микола Никифорович
Byts, Y. V.
Butenko, G. M.
Reznikov, O. G.
Danylova, L. Ya.
Pototska, I. I.
Horban, V. O.
Simeonova, N. K.
Kostenko, V. O.
Костенко Віталій Олександрович та ін.
Krishtal, Nikolay Vasylovych \ed.\
Mikhnev, Volodymyr Anatoliyovych \ed.\

Примірників всього: 1
Наук.Аб. (1)
Вільні: Наук.Аб. (1)

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   616.9
   І-74


    Pediatric Infectious Diseases : textbook [for students of higher medical educational establishments] / ed. S. O. Kramarov, O. B. Nadraga ; S. O. Kramarov, O. B. Nadraga, L. V. Pypa et al. - 4th ed. - K. : Medicine Publishing, 2020. - 238 p. : табл. - На англ. мові. - References: p. 238. - ISBN 978-617-505-807-7 : 160.00 грн
Переклад назви: Інфекційні хвороби у дітей: підручник для студентів вищих мед. навч. закладів / за ред. С. Крамарьова, О. Надраги

ДРНТІ	76.29.50	76.29.47
УДК	616.9-053.2(075.8)

Рубрики: ІНФЕКЦІЙНІ ХВОРОБИ(АНГЛ)--Підручник

ДІТИ(АНГЛ)--Підручник

Кл.слова (ненормовані):
Педіатрія -- national textbook -- національний підручник -- підручники
Анотація: The textbook presents classical and new data on pediatric infectious diseases, contemporary information on etiology, pathogenesis, clinical presentation, and methods of diagnosis; treatments for the most widely spread infectious diseases of children in Ukraine. Every topic is followed by a list of questions and tests for self-control of acquired knowledge. For students and interns of higher medical educational establishments. Foreword Measles Rubella Varicella Mumps Infection Pertussis Diphtheria Streptococcal Infection Acute Respiratory Viral Infections Poliomyelitis Herpetic infection Cytomegaloviral Infection Infectious Mononucleosis Meningococcal Infection Purulent Meningitis Acute Intestinal Infections Yersinial Infection Viral Hepatitis HIV Infection Fundamentals of Vaccinal Prevention References
Дод.точки доступу:
Kramarov, Serhiy Oleksandrovych
Крамарьов Сергій Олександрович
Nadraga, Oleksandr Bohdanovych
Надрага Олександр Богданович
Pypa, Larysa Volodymyrivna
Пипа Лариса Володимирівна
Kharchenko, Y. P.
Харченко Юрій Петрович
Lytvynenko, N. G.
Литвиненко Наталія Григорівна
Palatna, L. O.
Палатна Людмила Олександрівна
Shpak, I. V.
Шпак Ірина Володимирівна
Doroshenko, V. O.
Дорошенко Віталій Олександрович
Voronov, О.О.
Воронов Олександр Олександрович
Lysheniuk, S. A.
Лишенюк Світлана Адамівна
Shostakovych-Koretska, L. R.
Шостакович-Корецька Людмила Романівна
Chernyshova, L. I.
Kramarov, Serhiy Oleksandrovych \ed.\
Nadraga, Oleksandr Bohdanovych \ed.\

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   577.1
   Б 63


    Biological and Bioorganic Chemistry. In 2 books : national textbook. Book 1. Bioorganic Chemistry / B. S. Zimenkovsky, V. A. Muzychenko, I. V. Nizhenkovska, Q. O. Syrova ; ed. B. S. Zimenkovsky, I. V. Nizhenkovska. - 3rd ed. - K. : Medicine Publishing, 2020. - 287 p. - На англ. мові. - Бібліогр.: с. 272. - Index: с. 273-287. - ISBN 978-617-505-791-9 : 260.00 грн.
Переклад назви: Біологічна і біоорганічна хімія. В 2-х кн. Кн. 1: Біоорганічна хімія: підручник / Б. С. Зіменковський, В. А. Музиченко, І. В. Ніженковська, Г. О. Сирова

УДК

577.1(075.8)

Рубрики: БІОХІМІЯ(англ)--Підручник

Кл.слова (ненормовані):
підручники(англ) -- національні підручники -- national textbook
Анотація: The textbook contains the information about the structure, chemical properties and biological role of organic compounds which take part in human metabolic processes: low-molecular bioregulators (vitamins, hormones, other natural and synthetic biologically active compounds, including certain medications and toxic compounds) and biopolymers (carbohydrates, proteins and nucleic acids). This textbook is recommended for students and teachers of higher medical education establishments. PART І. THEORETICAL BASIS OF ORGANIC AND BIOORGANIC CHEMISTRY. THE STRUCTURE OF ORGANIC AND BIOORGANIC COMPOUNDS Сhapter 1. Classification and Nomenclature of Organic Compounds 1.1. Classification of Organic Compounds 1.1.1. Classification Based on the Carbon Chain Structure 1.1.2. Classification Based on the Nature of the Functional Group 1.2. Nomenclature of Organic Compounds Сhapter 2. The Structure of Organic Compounds 2.1. Representation of the Structure of Organic Compounds 2.2. Isomerism of Organic Compounds 2.2.1. Structural Isomerism 2.2.2. Stereoisomerism Сhapter 3. Electronic Conceptions in Organic Chemistry 3.1. Chemical Bonds in Bioorganic Molecules 3.1.1. The Structure of Covalent Bonds 3.1.2. Сharacteristics of Covalent Bonds 3.2. Electronic Effects, the Mutual Effect of Atoms in Molecules 3.2.1. The Inductive Effect 3.2.2. The Mesomeric Effect 3.3. Classification of Chemical Reactions and Reagents. the Mechanism of Chemical Reactions 3.3.1. Classification of Chemical Reactions Based on Their Mechanisms 3.3.2. Classification of Chemical Reactions Based on the Bond Cleavage 3.3.3. The Mechanisms of Chemical Reactions 3.4. The Acid and Base Properties of Organic Compounds 3.4.1. The Theory of Bronsted 3.4.2. The Theory of Lewis PART ІI. HYDROCARBONS AND THEIR DERIVATIVES Сhapter 4. Acyclic Hydrocarbons 4.1. Alkanes 4.1.1. The Structure, Homology, Nomenclature, and Isomerism 4.1.2. Chemical Properties 4.1.3. Industrial and Biomedical Significance 4.2. Alkenes 4.2.1. The Structure, Nomenclature and Isomerism 4.2.2. Chemical Properties 4.3. Alkynes 4.4. Alkadienes Сhapter 5. Carbocyclic Hydrocarbons 5.1. Alicyclic Hydrocarbons 5.1.1. Classification and Nomenclature 5.1.2. Chemical Properties 5.1.3. Biomedical Significance 5.2. Arenes 5.2.1. Classification, Aromaticity 5.2.2. Nomenclature and Isomerism of Mononuclear Arenes 5.2.3. Chemical Properties of Mononuclear Arenes 5.2.4. Polynuclear Arenes Сhapter 6. Halogen Derivatives of Hydrocarbons 6.1. Chemical Properties 6.1.1. Reactions of Nucleophilic Substitution 6.1.2. Reactions of Elimination 6.2. Biomedical Significance Сhapter 7. Hydroxyl Derivatives of Nydrocarbons. Thiols 7.1. Monoatomic Alcohols 7.1.1. Structure, Nomenclature and Isomerism 7.1.2. Chemical Properties 7.1.3. Individual Representatives 7.2. DI- and Polyatomic Alcohols 7.2.1. Structure, Nomenclature and Isomerism 7.2.2. Chemical Properties 7.2.3. Individual Representatives 7.3. Thiols and Thio Ethers 7.3.1. Structure and Nomenclature 7.3.2. Chemical Properties 7.4. Phenols 7.4.1. Structure, Classification and Nomenclature 7.4.2. Chemical Properties 7.4.3. Medical Application Сhapter 8. Amines 8.1. Classification and Nomenclature 8.2. Chemical Properties 8.3. Biological Activity and Toxicity Сhapter 9. Biologically Important Carbonyl Compounds 9.1. Structure and Nomenclature 9.2. Chemical Properties 9.2.1. Oxidation and Reduction Reactions 9.2.2. Reactions of Nucleophilic Addition 9.2.3. Reactions of the Addition-Elimination 9.2.4. Condensation Reactions 9.2.5. α-Carbon Atom Reactions 9.2.6. Polymerization Reactions 9.3. Biomedical Significance Сhapter 10. Carboxylic Acids and Their Functional Derivatives 10.1. Aliphatic and Aromatic Monocarboxylic Acids 10.1.1. Nomenclature 10.1.2. Chemical Properties 10.2. Carbonic Acid Derivatives 10.3. Aliphatic and Aromatic Dicarboxylic Acids 10.3.1. Classification and Nomenclature 10.3.2. Chemical Properties Сhapter 11. Biologically Important Heterofunctional Compounds 11.1. Hydroxy Derivatives of Amines 11.1.1. Amino Alcohols 11.1.2. Aminophenols 11.2. Hydroxy Acids 11.2.1. Aliphatic Hydroxy Acids 11.2.2. Aromatic Hydroxy Acids 11.3. Oxoacids 11.3.1. Some Representatives of Oxoacids 11.3.2. Biosynthesis of Higher Fatty Acids 11.4. Amino Acids 11.4.1. Structure of Amino Acids 11.4.2. Nomenclature and Isomerism of Amino Acids 11.4.3. Chemical Properties 11.5. Derivatives of Para-Amino Benzoic and Sulfanilic Acids PART ІII. BIOLOGICALLY ACTIVE HETEROCYCLIC COMPOUNDS Сhapter 12. Three-, Four- and Five-Membered Heterocyclic Compounds 12.1. Three- and Four-Membered Heterocyclic Compounds 12.2. Five-Membered Heterocycles Containing One Heteroatom 12.2.1. Chemical Properties 12.2.2. Some Representatives Having Biomedical Significance 12.3. Five-Membered Heterocycles Containing Two Heteroatoms 12.3.1. Oxazole and Isooxazole 12.3.2. Thiazole 12.3.3. Pyrazole 12.3.4. The Most Important Derivatives of Pyrazole 12.3.5. Imidazole 12.3.6. The Most Important Derivatives of Imidazole Сhapter 13. Six- and Seven-Membered Heterocyclic Compounds 13.1. Six-Membered Heterocycles Containing One Heteroatom 13.1.1. Six-Membered Heterocycles With Nitrogen Heteroatom 13.1.2. Six-Membered Heterocycles With Oxygen Heteroatom 13.2. Six-Membered Heterocycles Containing Two Heteroatoms 13.2.1. Six-Membered Heterocycles With Two Nitrogen Heteroatoms 13.2.2. Six-Membered Heterocycles With Nitrogen and Sulfur Heteroatoms 13.3. Seven-Membered Heterocycles Сhapter 14. Biologically Important Condensed Heterocyclic Systems, Alkaloids 14.1. Purine Derivatives 14.1.1. Hydroxy Derivatives of Purine 14.1.2. Amino Derivatives of Purine 14.2. Pteridine Derivatives 14.3. Alkaloids 14.3.3. Pyridine and Piperidine Alkaloids 14.3.2. Quinoline Alkaloids 14.3.3. Isoquinoline and Phenanthrene Isoquinoline Alkaloids 14.3.4. Tropane Alkaloids PART ІV. BIOPOLYMERS AND BIOREGULATORS Сhapter 15. Carbohydrates or Saccharides (Sugars) 15.1. Monosaccharides (Monoses) 15.1.1. Isomerism 15.1.2. Tautomerism 15.1.3. Chemical Properties 15.1.4. Individual Representatives 15.1.5. Derivatives of Monosaccharides 15.2. Disaccharides 15.2.1. Reducing Disaccharides 15.2.2. Non-Rreducing Disaccharides 15.3. Higher Polysaccharides 15.3.1. Homopolysaccharides 15.3.2. Heteropolysaccharides Сhapter 16. Proteinogenic Amino Acids, Peptides and Proteins 16.1. Proteinogenic Amino Acids and Their Properties 16.1.1. Isomerism and Structure 16.1.2. Chemical Properties 16.2. Peptides and Proteins 16.2.1. Amino Acid Composition and Amino Acid Sequence 16.2.2. Structural Organization of Proteins 16.2.3. Electrophoresis of Amino Acids and Proteins 16.2.4. Classification of Proteins 16.2.5. Qualitative Reactions on Proteins Сhapter 17. Nucleic Acids. Coenzymes 17.1. Nucleosides 17.2. Nucleotides 17.3. The Structure of Nucleic Acids 17.3.1. The Primary Structure 17.3.2. The Secondary Structure of DNA 17.3.3. The Structure and Functions of RNA 17.4. Nucleotide Coenzymes Сhapter 18. Lipids 18.1. Saponifiable Lipids 18.1.1. Simple Saponifiable Lipids 18.1.2. Complex Saponifiable Lipids 18.2. Nonsaponifiable Lipids 18.2.1. Terpenes 18.2.2. Carotenoids 18.2.3. Steroids 18.2.4. Prostaglandins Answer on the Test for Self Control Recommended Literature List Index
Дод.точки доступу:
Zimenkovsky, Boris Semenovich
Зіменковський Борис Семенович
Muzychenko, Volodymyr Afanasiiovych
Музиченко Володимир Опанасович
Nizhenkovska, Iryna Volodymyrivna
Ніженковська Ірина Володимирівна
Syrova, Ganna Olegivna
Сирова Ганна Олегівна
Zimenkovsky, Boris Semenovich \ред.\
Nizhenkovska, Iryna Volodymyrivna \ред.\

Примірників всього: 14
Наук.Аб. (3), Уч.Аб. (5), ННА (6)
Вільні: Наук.Аб. (3), Уч.Аб. (5), ННА (6)

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   577.1
   Б 63


    Biological and bioorganic chemistry. In 2 books : [textbook for students of higher medical educational establishments]. Book 2. Biological chemistry / ed. Yu. I. Gubsky, I. V. Nizhenkovska ; Yu. I. Gubsky, I. V. Nizhenkovska, M. M. Korda et al. - 2nd ed. - K. : Medicine Publishing, 2021. - 542 p. : il. - На англ. мові. - Index: p. 535-541. - References: p. 542. - ISBN 978-617-505-886-2 : 360.00 грн.
Переклад назви: Біологічна та біоорганічна хімія. В 2-х кн. Кн. 2. Біологічна хімія: підручник / за ред. Ю. Губського, І. Ніженковської

УДК

577.1(075.8)

Рубрики: БІОХІМІЯ(АНГЛ)--Підручник

Кл.слова (ненормовані):
national textbook -- підручники англійською
Анотація: This textbook contains a systematic presentation of the course of biological chemistry according to the educational program for students of higher medical (pharmaceutical) educational establishments. The core text of this book examines the structure of an enzyme, and the metabolic pathways of the major classes of biomolecules (proteins, amino acids, carbohydrates, lipids, nucleotides, porphyrins); structural features and properties of nucleic acids, DNA and RNA; molecular biology and genetics, biochemical foundations of the physiological functions of the human body and their neurohumoral regulation are highlighted. Considerable attention is paid to the molecular mechanisms underlying the functions of blood cells, liver, kidneys, muscles, connective tissue, immune and nervous systems. The biochemical basis of the pathogenesis of atherosclerosis, diabetes mellitus, obesity, diseases of the endocrine, immune, nervous systems and connective tissue are considered. In addition to informational material, each chapter of the textbook contains tests and tasks for self-control. Introduction. History of development of biochemistry PART I. GENERAL PRINCIPLES OF REGULATION OF METABOLISM Chapter 1. Biomolecules and cellular structures 1.1. Chemical composition of living organism 1.2. Biomolecules and their functions 1.3. Scheme of structure of prokaryotic and eukaryotic cells 1.4. Biological membranes Chapter 2. Enzymes 2.1. Enzymes: structure, properties and classification 2.2. Mechanism of the enzyme action 2.3. Kinetics of enzymatic reactions. The units of enzymatic activity 2.4. Regulation of enzymatic processes 2.5. Medical enzymology 2.6. Cofactors and coenzymes: chemical structure and functions Chapter 3. Fundamental regularities of metabolism. Tricarboxylic acid cycle 3.1. Common pathways of protein, lipid, and carbohydrate metabolism 3.2. Oxidative decarboxylation of pyruvic acid 3.3. Tricarboxylic acid cycle or Krebs cycle Chapter 4. Molecular foundations of bioenergetics 4.1. Pathways of the oxygen consumption in the reactions of biological oxidation 4.2. Tissue respiration 4.3. Chemiosmotic mechanism of ATP synthesis in mitochondria 4.4. Non-phosphorylative oxidation in electron trasport chain as the mechanism of heat production in the mitochondria 4.5. Inhibitors and uncouplers of oxidative phosphorylation Chapter 5. Hormonal regulation of metabolism 5.1. General characteristics of hormones 5.2. Classification of hormones 5.3. Mechanism of action of hydrophilic hormones 5.4. Mechanism of action of hormones that interact with the intracellular receptors 5.5. Regulation of secretion of hormones PART II. CARBOHYDRATE, LIPID AND AMINO ACID METABOLISM. REGULATION OF CARBOHYDRATE, LIPID AND AMINO ACID METABOLISM Chapter 6. Carbohydrate metabolism. Regulation of carbohydrate metabolism 6.1. Glycolysis 6.2. Alcohol fermentation 6.3. Pentose phosphate pathway of glucose metabolism 6.4. Metabolism of fructose 6.5. Metabolism of sorbitol 6.6. Metabolism of galactose 6.7. Gluconeogenesis 6.8. Metabolism of glycogen 6.9. Regulation of glycogenolysis and glycogenesis Chapter 7. Lipid metabolism. Regulation of lipid metabolism 7.1. Metabolism of triacylglycerols 7.2. Metabolism of fatty acids 7.3. Metabolism of glycerol 7.4. Ketone body formation and utilization in normal and pathological conditions 7.5. Metabolism of phospholipids 7.6. Metabolism of cholesterol 7.7. Disorders of lipid metabolism Chapter 8. Amino acid metabolism. Enzymopathies of amino acid metabolism 8.1. General pathways of amino acids transformation 8.2. Formation and detoxification of ammonia. Urea cycle 8.3. Specialized pathways of acyclic and cyclic amino acids 8.4. Biosynthesis of porphyrins 8.5. Hereditary disorder of porphyrin metabolism PART III. MOLECULAR BIOLOGY. BIOCHEMISTRY OF INTERCELLULAR COMMUNICATIONS Chapter 9. Metabolism of nucleotides 9.1. Biosynthesis and catabolism of purine and pyrimidine nucleotides 9.2. Disorders of purine and pyrimidine metabolism Chapter 10. Fundamentals of molecular biology 10.1. Structure of deoxyribonucleic acid 10.2. Biosynthesis of deoxyribonucleic acid 10.3. Biosynthesis of ribonucleic acid (RNA) 10.4. Ribosomal protein syntesis (translation) 10.5. Antibiotics are inhibitors of template synthesis 10.6. Viruses and toxins are inhibitors of template synthesis in eukaryotic cells 10.7. Biochemical mechanism of antiviral effect of interferons Chapter 11. Fundamentals of molecular genetics 11.1. Phases of eukaryotic cell cycle. Biochemical mechanism of control of cell entry into mitosis 11.2. Molecular mechanism of mutations 11.3. Genetic recombinations 11.4. Amplification of genes (genes of metallothionein, dihydrofolate reductase) 11.5. Genetic engineering: some basic concepts, biomedical significance Chapter 12. Biochemistry of hormonal regulation 12.1. Hormones of hypotalamic-pituitary system 12.2. Pancreatic hormones 12.3. Hormones of digestive system 12.4. Hormones of thyroid gland 12.5. Hormonal regulation of calcium homeostasis 12.6. Steroid hormones of adrenal glands and gonads 12.7. Biological active eicosanoids 12.8. Eicosanoids in the inflammation Part IV. FUNCTIONAL BIOCHEMISTRY Chapter 13. Biochemystry of human nutrition 13.1. Macronutrients 13.2. Biochemical role of microelements 13.3. Digestion of nutrients in the digestive tract 13.4. Violations of digestion in alimentary canal 13.5. Vitamins Chapter 14. Biochemistry of blood 14.1. Respiratory function of red blood cells 14.2. Normal and pathological forms of hemoglobin 14.3. Acid-base balance and buffer systems of blood 14.4. Non-protein components of plasma 14.5. Blood proteins 14.6. Blood plasma lipoproteins 14.7. Blood coagulation, anticoagulant and fibrinolytic systems Chapter 15. Biochemistry of immune processes 15.1. Immunoglobulins: structure, biological functions 15.2. Mediators and hormones of immune system 15.3. Biochemical components of human complement system 15.4. Biochemical mechanisms of development of immunodeficiency Chapter 16. Biochemical functions of the liver 16.1. Bile formation in liver 16.2. Metabolism of bile pigments in the liver 16.3. Pathobiochemistry ofjaundice 16.4. Biochemical disturbances in certain liver diseases 16.5. Biotransformation of xenobiotics and endogenous toxins Chapter 17. Biochemical functions of the kidneys 17.1. Steps of urine formation 17.2. Physical characteristics of urine 17.3. Chemical composition of urine 17.4. Role of the kidneys in acid-base balance 17.5. Features of kidney metabolism 17.6. Biochemical tests of kidney function Chapter 18. Biochemistry of muscles 18.1. Structure of myofibrils 18.2. Chemical composition of muscle tissue 18.3. Biochemical features of cardiac and smooth muscles 18.4. Biochemical mechanisms of contraction and relaxation of muscles 18.5. Sources of energy for muscle constractions 18.6. Biochemical changes in muscle pathology Chapter 19. Biochemistry of connective tissue 19.1. Structure and metabolism of collagen 19.2. Elastin structure 19.3. Structure and metabolism of proteoglycans 19.4. Structure of glycoproteins Chapter 20. Biochemistry of nervous system 20.1. Chemical composition of the nervous system 20.2. Nervous tissue metabolism 20.3. Molecular basis of bioelectrical processes on the membrane of neurons 20.4. Neurotransmitters 20.5. Metabolism of neurotransmitters and neuromodulators in mental disorders 20.6. Neurochemical mechanisms of psychotropic drugs Answers for tests for self-control Index References
Дод.точки доступу:
Gubsky, Yuriy I.
Губський Юрій Іванович
Nizhenkovska, Iryna Volodymyrivna
Ніженковська Ірина Володимирівна
Korda, Mykhaylo Mykhaylovych
Корда Михайло Михайлович
Borzenko, B. G.
Brazaluk, O. Z.
Ersteniuk, G. M.
Efetov, K. O.
Zhukov, V. I.
Zaichko, N. V.
Komarevtseva, I. O.
Lutsyuk, M. B.
Neporada, K. S.
Непорада Каріне Степанівна
Tarasenko, L. M.
Тарасенко Лідія Максимівна et al.
Gubsky, Yuriy I. \ed.\
Nizhenkovska, Iryna Volodymyrivna \ed.\

Примірників всього: 3
Наук.Аб. (3)
Вільні: Наук.Аб. (3)

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   616.1/9
   С 37


    Family Medicine. In 3 books : textbook [for students of higher medical educational establishments]. Book 3. Special Part. Multidisciplinary General Medical Practice / ed. O. M. Hyrina, L. M. Pasiyeshvili, L. S. Babinets ; L. S. Babinets, P. A. Bezditko, S. A. Bondar et al. - K. : Medicine Publishing, 2020. - 615 p. : il. ; 25 cm. - На англ. мові. - ISBN 978-617-505-493-2(edition in 3 books). - ISBN 978-617-505-799-5 (Вооk 3) : 695.00 грн.
Переклад назви: Сімейна медицина. В 3-х кн. Кн. 3. Спеціальна частина. Поліпрофільність загальної лікарської практики: підручник / за ред. О. М. Гиріної, Л. М. Пасієшвілі, Л. С. Бабінець

УДК

616.1/9:614.254.3(075.8)

Рубрики: ТЕРАПІЯ(англ)

СІМЕЙНА ПРАКТИКА(англ)--Підручник

Кл.слова (ненормовані):
підручники -- national textbook -- національний підручник
Анотація: The textbook is committed to provide current information regarding family physician practice, considering the multidisciplinary aspect of general medical practice. The textbook contains practical recommendations for family physicians in the management of patients with nosologies at the stage of primary medical care, focuses on the clinical manifestations, diagnostic criteria, treatment and prevention algorithms within the occupational competence framework of family physician, as well as the guidelines for interaction with healthcare professionals who provide specialized care. The textbook corresponds to the curriculum on the specialty «General Practice/Family Medicine» and is intended for use by students of higher medical educational establishments, internship doctors, family physicians/GPs and pediatricians List of abbreviations...................... 8 Chapter 1. Obstetrics.................... 9 1.1. Anatomy and physiology of female body (V.H. Karpenko)...... 9 1.1.1. Anatomy of female reproductive system............ 9 1.1.2. Main female sex hormones................. 9 1.1.3. Diagnosis of early pregnancy............... 10 1.2. Check up and prenatal care of pregnant (O.O. Vorontsov)... 13 1.3. Prenatal psychoprophylactic training of responsible paternity...22 1.4. Drug therapy in pregnancy................ 25 1.5. Early gestosis (V.H. Karpenko)................ 30 1.5.1. Rare forms of early gestosis.............. 33 1.5.2. Treatment of early gestosis................ 34 1.6. Late gestosis (V.H. Karpenko).............. 36 1.7. Postpartum period (L.S. Babinets)..............41 Chapter 2. Gynecology.....................42 2.1. Tumors of genital organs (V.H. Karpenko)...........42 2.1.1. Tumors of external genitalia................42 2.1.2. Tumors of vagina................... 43 2.1.3. Tumors of the cervix................. 44 2.2. Dysfunctional (abnormal) uterine bleeding.......... 46 2.3. Disorders of sex development in children and adolescents... 51 2.3.1. Delayed puberty.................... 53 2.4. Inflammatory genital diseases in girls and adolescent girls....55 2.5. Female genital inflammatory diseases...........57 2.6. Perimenopause..................... 59 2.7. Family planning (N.M. Pasiyeshvili)............ 68 2.7.1. Types of contraception................ 68 2.7.2. Family planning issues................. 81 2.7.3. Topical issues of infertile couple............... 84 Chapter 3. Allergology................... 87 3.1. Allergic rhinitis (N.M. Zhelezniakova)............. 89 3.2. Urticaria......................... 92 3.3. Food allergy..................... 93 3.4. Pollinosis (T.M. Pasiyeshvili)................. 99 3.4.1. Pollinosis in children................. 100 3.5. Pharmacotherapy of allergic diseases (N.M. Zhelezniakova)... 103 Chapter 4. Systemic allergic vasculitis (V.M. Zhdan, M.Yu. Babanina)... 110 Chapter 5. Dermatology (S.A. Bondar)............ 126 5.1. Pyodermatites...................... 126 5.1.1. Features of clinical forms................ 127 5.1.2. Treatment and prevention of pyodermia......... 130 5.2. Mycoses........................ 131 5.2.1. Keratomycosis..................... 132 5.2.2. Pseudomycosis................... 132 5.2.3. Dermatophytosis.................... 133 5.2.4. Candidosis.................... 136 5.3. Parasitic skin diseases (dermatozoonoses).......... 137 5.3.1. Pediculosis.................... 137 5.3.2. Scabies...................... 138 5.4. Viral dermatoses.................... 139 5.4.1. Catarrhal fever (Herpes simplex)............. 139 5.4.2. Shingles (Herpes zoster)................ 140 5.4.3. Warts (verrucae).................... 141 5.5. Allergic skin diseases.................. 141 5.5.1. Dermatites.................... 141 5.5.2. Eczema...................... 145 5.5.3. Atopic dermatitis.................... 147 5.5.4. Psoriasis....................... 150 5.6. Sexually transmitted infections (A.A. Nalizhytyi)........ 152 5.6.1. Syphilis...................... 152 Chapter 6. Neurology (O.L. Tovazhnianska)........... 159 6.1. Headache..................... 159 6.1.1. Primary headache................. 159 6.1.2. Secondary headache.................. 160 6.1.3. Headache diagnosis and patient’s route........... 161 6.1.4. Headache treatment................. 161 6.2. Acute disorder of cerebral circulation............ 162 6.3. Encephalopathic syndrome............... 167 6.4. Paroxysmal neurological conditions........... 169 6.4.1. Epileptic seizure.................... 169 6.4.2. Paroxysmal states of nonepileptic origin.......... 170 6.5. Syndromes of the peripheral nervous system disorders.... 172 6.6. Neurological syndromes caused by somatic pathology...... 175 Chapter 7. Basics of geriatrics and gerontopharmacology (A.A. Zazdravnov)...184 Chapter 8. Otorhinolaryngology (S.M. Pukhlyk)........... 193 8.1. Ear pain........................193 8.1.1. Diseases accompanied by otalgia............193 8.1.2. Inflammatory diseases of the outer and middle ear.......195 8.1.3. Neoplasms of the external auditory canal and middle ear....198 8.2. Pain in the pharynx....................199 8.2.1. Diseases accompanied by sore throat........... 199 8.2.2. Inflammatory diseases of the pharynx............ 201 8.2.3. Malignant pharyngeal tumors..............208 8.2.4. Malignant neoplasms of the larynx............208 8.3. Disorders of nasal breathing...............209 8.3.1. Inflammatory diseases of the nose............209 8.3.2. Inflammatory diseases of the sinuses (sinusitis).......213 8.3.3. Foreign bodies in the nasal cavity.............215 8.3.4. Nasal and nasopharyngeal neoplasms.......... 216 8.3.5. Nasal septal injuries...................217 8.3.6. Adenoid hypertrophy..................218 8.3.7. Nasal injuries.....................218 8.3.8. Difficulty laryngeal breathing...............219 8.4. Nasal bleeding......................223 8.5. Hearing loss......................224 8.5.1. Diseases accompanied by hearing loss..........225 8.6. Purulent discharge from the ear................229 8.6.1. Diseases associated with purulent discharge from the ear...230 8.6.2. Malignant tumors of nasal cavity and sinuses..........231 8.7. Voice disorders....................232 8.8. Rhinolalia.......................234 Chapter 9. Ophthalmology (P.A. Bezditko).............236 9.1. Refractive errors in children and adults.............236 9.2. Diseases of conjunctiva...................238 9.2.1. Inflammatory conjunctival diseases of exogenous etiology...238 9.2.2. Allergic conjunctivitis..................243 9.2.3. Degenerative dystrophic conjunctival changes........245 9.2.4. Tumors of conjunctiva...................246 9.3. Eyelid diseases....................246 9.3.1. Congenital anomalies of the eyelids.............247 9.3.2. Acquired diseases of the eyelids..............248 9.3.3. Tumors of the eyelids.................250 9.4. Diseases of the lacrimal organs............... 251 9.4.1. Congenital diseases of the lacrimal organs...........251 9.4.2. Neoplasms of the lacrimal passages............252 9.5. Corneal diseases....................253 9.5.1. Subjective and objective symptoms..............253 9.5.2. Characteristic clinical forms.................254 9.6. Uveal diseases.....................258 9.6.1. Choroidal inflammatory diseases..............258 9.6.2. Choroidal neoplasms.................260 9.7. Lens diseases......................261 9.7.1. Congenital cataract....................261 9.7.2. Acquired lens opacity..................262 9.7.3. Lens dislocation....................263 9.7.4. Presentday methods of lens diseases treatment.........264 9.8. Glaucoma.......................264 9.8.1. Primary glaucoma....................264 9.8.2. Secondary glaucoma..................270 9.8.3. Congenital glaucoma..................271 9.9. Retinal diseases......................273 9.9.1. Retinal vascular disease..................273 9.9.2. Acute circulatory disorders of the retinal vessels.........275 9.9.3. Diabetic retinopathy....................277 9.9.4. Retinal and chorioretinal degeneration............278 9.9.5. Hereditary retinal degeneration..............279 9.9.6. Retinal inflammatory diseases............... 281 9.9.7. Retinal detachment....................282 9.9.8. Tumors of the retina....................283 9.9.9. Retinal damage in patients with AIDS............284 9.10. Optic nerve diseases...................285 9.10.1. Inflammatory diseases of the optic nerve..........285 9.10.2. Toxic (dystrophic) lesions of the optic nerve........286 9.10.3. Vascular diseases of the visual analyzer...........287 9.10.4. Choked disc.....................288 9.10.5. Atrophy of the optic nerve...............288 9.10.6. Optic nerve tumors...................289 9.10.7. Developmental abnormalities of the optic nerve.........290 9.11. Orbit diseases......................290 9.12. Visual organ injuries..................292 9.12.1. Mechanical injuries....................292 9.12.2. Eye burns......................295 9.12.3. Ultraviolet damage to the eyes..............297 Chapter 10. Pediatrics.....................299 10.1. Anatomy and physiology of newborn and neonatal care (Ya. I. Venher)...299 10.1.1. Anatomy and physiology of child in the neonatal period......299 10.1.2. Physiological (transient) states in the neonatal period......300 10.1.3. Newborn sleep......................307 10.1.4. Primary examination of child after discharge from the maternity unit.308 10.1.5. Newborn care...................... 309 10.1.6. Hygiene rules to follow with children of the first year of life....310 10.2. Breastfeeding a newborn (V.I. Velychko)............313 10.2.1. Qualitative and quantitative composition of breast milk......314 10.2.2. Regimen and diet of nursing woman.............315 10.3. Feeding children of the first year of life (H.O. Danylchuk, N.S. Shnayder).320 10.3.1. Feeding on demand....................320 10.3.2. Introduction of complementary foods in breastfeeding period.....323 10.3.3. Premature baby feeding.................327 10.3.4. Formula feeding....................331 10.3.5. Mixed feeding.....................339 10.4. Nutrition for children aged 1—3 years (V.I. Velychko)........340 10.5. Preventive vaccination (T.V. Frolova)...............345 10.5.1. Basics of vaccination...................345 10.5.2. Classification of vaccines..................345 10.5.3. Presentday vaccine components................347 10.5.4. Vaccines provided by family physician. Modern vaccination schedule.348 10.5.5. Key issues while providing vaccination............350 Chapter 11. Psychiatry (V.I. Korostiy)................. 352 11.1. Anxiety disorders......................352 11.1.1. Phobic anxiety disorders...................354 11.1.2. Other anxiety disorders..................356 11.1.3. Obsessivecompulsive disorder................357 11.1.4. Treatment program for anxiety disorders.............360 11.2. Depression.........................366 Chapter 12. Phthisiology (O.S. Shevchenko)..............377 12.1. Strategies for TB control..................377 12.2. TB prevention.......................378 12.2.1. Vaccination........................378 12.2.2. Chemoprophylaxis......................381 12.2.3. Infection control.......................382 12.3. Tuberculosis detection...................383 12.3.1. Active detection.....................385 12.3.2. Passive detection.....................389 12.3.3. Diagnosis of tuberculosis at different levels of medical care....391 12.3.4. Formulation of diagnosis...................395 12.4. TB treatment.........................398 Chapter 13. Surgery.......................405 13.1. Pediatric surgery (V.S. Konoplitskyi)..............405 13.1.1. Traumatic disease.....................405 13.1.2. Inflammatory and purulentseptic diseases in children.........412 13.1.3. Acute and chronic digestive tract diseases.............423 13.2. General surgery (L.S. Babinets, B.O. Mihenko)...........436 13.2.1. Wounds and wound infection................436 13.2.2. Breast diseases.....................443 13.2.3. Diseases of the thoracic and abdominal cavities.......... 448 13.2.4. Emergency surgical diseases of the abdominal cavity.........481 13.2.5. Purulent outpatient surgery...................501 13.2.6. Benign tumors......................515 13.3. Diseases of the great vessels (L.S. Babinets, B.O. Mihenko).......518 13.3.1. Lower limb varicose vein disease.................518 13.3.2. Acute superficial vein thrombophlebitis of the lower limbs.......520 13.3.3. Acute deep vein thrombosis of the lower limbs............521 13.3.4. Occlusive diseases of the lower limb great arteries........523 13.3.5. Postthrombophlebic lower limb syndrome..............526 13.3.6. Thrombosis and embolism of the upper and lower peripheral arteries (acute arterial insufficiency)............................528 13.3.7. Acute embolism and thrombosis of mesenteric vessels (acute mesenteric ischemia)...........................530 13.4. Proctology (T.I. Tamm).....................531 13.4.1. Acute and chronic proctological diseases..............531 13.4.2. Diarrhealinflammatory syndrome...............542 13.4.3. Rectal prolapse syndrome...................548 13.5. Thermal and chemical damage (B.O. Mihenko, L.S. Babinets)......549 13.5.1. Thermal burns.......................550 13.5.2. Chemical burns........................554 13.5.3. Electrical injury......................555 13.5.4. Cold injury..........................555 13.6. Traumatology and orthopedics (B.O. Mihenko, L.S. Babinets)......559 13.6.1. Acute damage to bones and joints................559 13.6.2. Congenital and chronic lesions of bones and joints........572 13.7. Urology (V.M. Lisovyi, I.A. Harahatyi)...............586 13.7.1. Dysuric disorders, urinary incontinence..............586 13.7.2. Infectious and inflammatory diseases of the genitourinary system....588 13.7.3. Prostate gland enlargement.................596 13.7.4. Emergency care in urological diseases...............601 Annexes.............................610
Дод.точки доступу:
Babinets, L. S.
Бабінець, Л. С.
Bezditko, P. A.
Бездітко, Павло Андрійович
Bodnar, S. A.
Боднар, С. А.
Velychko, Valentyna Ivanivna
Величко, Валентина Іванівна
Venger, Ya. I.
Венгер, Я. І.
Vorontsov, O. O.
Воронцов, О. О.
Harahatyi, I. A.
Zhelezniakova, N. M.
Железнякова Н. М.
Zazdravnov, A. A.
Karpenko, V. H.
Barna, Olha Mykolayivna
Барна Ольга Миколаївна
Zhdan, V. M.
Ждан, Вячеслав Миколайович
Babanina, M. Yu.
Бабаніна, Марина Юріївна
Danylchuk, H. O. та ін.
Hyrina, Olha Mykolayivna \ed.\
Гиріна, Ольга Миколаївна
Pasiyeshvili, Liudmyla Mykhailivna \ed.\
Пасієшвілі, Людмила Михайлівна
Babinets, L. S. \ed.\

Примірників всього: 50
ЧЗ (1), Наук.Аб. (3), Гурт.4 (1), Уч.Аб. (45)
Вільні: ЧЗ (1), Наук.Аб. (3), Гурт.4 (1), Уч.Аб. (45)

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   616-092
   П 20


    Pathophysiology : textbook [for students of higher medical educational establishments] / ed. N. V. Krishtal, V. A. Mikhnev ; N. V. Krishtal, V. A. Mikhnev, N. N. Zayko et al. - 3rd ed. - K. : Medicine Publishing, 2019. - 655 p. : il. - На англ. мові. - References: p. 603-637. - Index: p. 638-655. - ISBN 978-617-505-759-9 : 695.00 грн., 650.00 грн.
Переклад назви: Патофізіологія: підручник / за ред. М. В. Кришталя, В. А. Міхньова

УДК

616-092(075.8)

Рубрики: ПАТОФІЗІОЛОГІЯ(англ)--Підручник

Кл.слова (ненормовані):
підручники -- national textbook
Анотація: The textbook is prepared by a team of staff at higher educational institutions and academic research institutions of Ukraine, who are recognized experts in various aspects of pathophysiology that gives reason this basic textbook to be national. It is recommended for English-speaking students of higher medical educational establishments. The textbook can be useful for teachers and physicians of all specialties. Abbreviations........................ 11 Preface........................... 14 Introduction (MD, PhD, DSc, Professor Nikolay N. Zayko).......15 The Subject and Tasks of Pathological Physiology............ 15 Relationship Between Pathological Physiology and Other Medical Sciences, Its Importance for Clinical Disciplines................ 15 Experiment as the Basic Method of Pathological Physiology........ 16 Historical Sketch of the Development of Pathological Physiology (MD, PhD, DSc, Professor Valentin F. Myslitskiy; MD, PhD, DSc, Professor Sergey V. Ziablitsev)...18 Part One GENERAL NOSOLOGY Chapter I. GENERAL THEORY OF DISEASES (MD, PhD, DSc, Professor Nikolay N. Zayko).............. 23 Health............................. 23 Disease............................. 24 Principles of Diseases Classification................. 25 Pathological Reaction, Pathological Process, Pathological Condition......26 Typical Pathological Processes......... 27 Main Periods (Stages) of Disease Development....... 27 Chapter II. ETIOLOGY AND PATHOGENESIS (MD, PhD, DSc, Professor Nikolay N. Zayko)..... 31 Etiology................... 31 Conditions of the Disease Occurrence...... 33 Pathogenesis................. 34 The Cause-and-Effect Relationship......... 35 General and Local.............. 36 Structure and Function............. 36 Nonspecific and Specific............ 36 Adaptation and Compensation.......... 37 Reactivity and its Role in Pathology (MD, PhD, DSc, Professor Liudmila Ya. Danilova) 38 Types of Resistance. Relations with Reactivity..... 39 Chapter III. PATHOGENIC EFFECT OF ENVIRONMENTAL FACTORS ON THE ORGANISM (MD, PhD, Associate Professor Natalia K. Simeonova) 41 Mechanical Trauma............. 41 Thermal Trauma............. 41 Barotrauma.............. 45 Radiation Injury.............. 46 Etiology............. 46 Pathogenesis............ 47 Acute Radiation Disease.......... 53 Chronic Radiation Disease........... 54 Electrotrauma.............. 55 Pathogenic Effect of Space Flight Factors....... 56 Chapter IV. THE ROLE OF HEREDITY, CONSTITUTION AND AGE IN PATHOLOGY (MD, PhD, Associate Professor Natalia K. Simeonova)....... 57 Genetically Determined Diseases........ 57 Classification............. 57 Etiology............. 58 Pathogenesis............ 59 Molecular Genetic (Hereditary) Diseases...... 60 Chromosomal Diseases.......... 65 Hereditary Predisposition........... 66 Genetic Examination of a Patient....... 66 Principles of Prevention and Treatment of Hereditary Diseases 69 Role of The Constitution in Pathology........ 70 Pathological Physiology of Fetal Development (MD, PhD, DSc, Professor Larisa A. Popova)...... 73 Ageing (MD, PhD, DSc, Professor Gennadiy M. Butenko)..... 74 Changes in the Body during Aging....... 77 Ageing and Diseases........... 82 Causes and Mechanisms of Ageing........ 83 The Ways of Influence on Ageing........ 84 Part Two GENERAL PATHOPHYSIOLOGY OF CELLS. TYPICAL METABOLIC DISORDERS Chapter V. PATHOPHYSIOLOGY OF CELL (MD, PhD, DSc, Professor Gennadiy M. Butenko)...... 86 Disturbances of Cells Functions........ 86 Disorders of Metabolic Processes and Environment Interaction... 87 Disturbance of Cell Energy Supply......... 88 Disturbances of Genetic Information Storage and Transfer. 89 Intracellular Synthesis Disorders......... 91 Dissimilation Interruption.......... 92 Cell Damage and Death............ 93 Chapter VI. PATHOLOGY OF ENERGY BALANCE (MD, PhD, DSc, Professor Liudmila Ya. Danilova; MD, PhD, DSc, Professor Nikolay V. Krishtal)..... 95 Chapter VII. PATHOPHYSIOLOGY OF CARBOHYDRATE METABOLISM (MD, PhD, DSc, Professor Liudmila Ya. Danilova; MD, PhD, DSc, Professor Nikolay V. Krishtal).... 98 Carbohydrate Metabolism and its Regulation...... 98 Pathology of the Carbohydrate Metabolism....... 100 Chapter VIII. Pathophysiology OF lipid METABOLISM (MD, PhD, DSc, Professor Nikolay V. Krishtal; MD, PhD, DSc, Professor Liudmila Ya. Danilova)... 105 Malabsorption of Lipids............ 105 Disorders of Lipid Transport and Deposition....... 105 Lipid Infiltration and Lipid Dystrophy...... 107 Disorder of Intermediate Lipid Metabolism...... 107 Disorders of Lipid Metabolism in The Adipose Tissue..... 108 Obesity................ 109 Weight Loss............... 114 Lipidoses.............. 115 Chapter IX. PATHOPHYSIOLOGY OF PROTEIN METABOLISM (MD, PhD, DSc, Professor Larisa A. Popova; MD, PhD, DSc, Professor Victor Ye. Dosenko).... 116 Disorders of Amino Acid Metabolism....... 116 Hereditary Disorders of Metabolism of Certain Amino Acids.. 117 Disorders of Final Stages of Protein Metabolism...... 119 Disorders of Proteins of the Blood....... 120 Disorders of the Nucleic Acids Metabolism...... 120 Chapter X. PATOPHYSIOLOGY OF ACID-BASE HOMEOSTASIS (MD, PhD, DSc, Professor Nikolay V. Krishtal)..... 122 Etiology, Pathogenesis and Forms of Acid-Base Imbalance.... 124 The Relationship between ABH and Mineral Exchange.... 124 Etiology and Classification of Non-Respiratory Acid-Base Imbalance 126 Pathological Effects of Acid-Base Imbalance on the Body.... 127 Mechanisms of Compensation of Acid-Base Imbalance.... 128 Chapter XI. PATOPHYSIOLOGY OF WATER-ELECTROLYTE BALANCE (MD, PhD, DSc, Professor Nikolay V. Krishtal; MD, PhD, DSc, Professor Oleg I. Sukmanskiy).... 132 Types, Causes, and Consequences of Water-Electrolyte Imbalance 136 Electrolyte Imbalance........... 142 The Exchange of Sodium and Its Imbalance....... 142 The Exchange of Potassium and Its Imbalance.... 143 The Exchange of Magnesium and Its Imbalance.... 144 The Exchange of Chlorine and Its Imbalance..... 145 The Exchange of Calcium and Its Imbalance...... 146 The Exchange of Phosphorus and Its Imbalance...... 148 The Osteoporosis............. 149 Chapter XII. PATHOPHYSIOLOGY OF MICROELEMENTS METABOLISM (MD, PhD, DSc, Professor Nikolay V. Krishtal)..... 151 Iron Exchange and Imbalance........... 152 Copper Exchange and Imbalance......... 156 Zinc Exchange and Imbalance........... 159 Manganese Exchange And Imbalance......... 161 Chromium Exchange and Imbalance.......... 162 Vanadium Exchange and Imbalance.......... 163 Molybdenum Exchange and Imbalance........ 165 Selenium Exchange and Imbalance.......... 165 Iodine Exchange And Imbalance......... 169 Fluoride Exchange and Imbalance.......... 171 Chapter XIII. PATHOPHYSIOLOGY OF VITAMINS METABOLISM (MD, PhD, DSc, Professor Nikolay V. Krishtal)..... 173 Classification and General Characteristics of Vitamins in the Human Body 173 Sources of Vitamins and Their Metabolism in the Body.... 177 Main Causes of Vitamin Deficiency Development..... 179 Deficiency of Antineurotic Vitamin В1........ 181 Deficiency of Riboflavin........... 182 Deficiency of Antipellagric Vitamin РР...... 182 Deficiency of Antidermatitic Vitamin В6...... 183 Deficiency of Folic Acid........... 184 Deficiency of Antianemic Vitamin В12...... 185 Deficiency of Antiscorbutic Vitamin C....... 186 Deficiency of Biotin............ 187 Deficiency of Rutin.......... 188 Deficiency of Antixerophthalmic Vitamin A...... 188 Deficiency of Antirachitic Vitamin D........ 188 Deficiency of Vitamin E......... 190 Deficiency of Vitamin F......... 191 Deficiency of Antihemorrhagic Vitamin K..... 192 Hypervitaminoses............. 192 Part Three TYPICAL PATHOLOGICAL PROCESSES Chapter XIV. Pathophysiology of peripheral blood CIRCULATION (MD, PhD, DSc, Professor Yuriy V. Byts; MD, PhD, DSc, Professor Anatoliy V. Kubyshkin).... 194 Arterial Hyperemia........... 196 Venous Hyperemia............. 201 Ischemia............... 202 Stasis.............. 206 Thrombosis............. 206 Embolism............... 209 Chapter XV. microcirculatory disorders (MD, PhD, DSc, Professor Yuriy V. Byts; MD, PhD, DSc, Professor Anatoliy V. Kubyshkin) 213 Intravascular Mechanisms of Microcirculatory Disorders.. 214 Extravascular Mechanisms of Microcirculatory Disorders.. 217 Chapter XVI. INFLAMMATION (MD, PhD, DSc, Professor Nikolay V. Krishtal) 218 Experimental Models of Inflammation......... 219 Etiology of Inflammation........... 220 Pathogenesis of Inflammation.......... 220 Alteration............. 221 The Inflammatory Cells and Mediators........ 225 The Influence of Inflammatory Mediators on the Organism. 233 Vascular Reactions in Inflammation....... 234 Exudation.............. 236 Emigration of the White Blood Cells...... 237 Phagocytosis.............. 242 Proliferation and Regeneration........ 244 Classification............ 249 Chapter XVII. PATHOPHYSIOLOGY OF THE IMMUNITY (MD, PhD, DSc, Professor Vladislav A. Horban; MD, PhD, DSc, Professor Nikolay V. Krishtal) 251 The Main Functions and Structure of the Immune System... 251 Genesis and Function of T- and B-Lymphocytes...... 253 Experimental Models of Hypofunction of the Immune System... 257 Immune Deficiency Diseases......... 257 Immune-Suppressive Diseases........ 263 Disorders of the Systems that Functionally Associated with the Immune System 264 Chapter XVIII. ALLERGY (MD, PhD, DSc, Professor Vladislav A. Horban) 267 Etiology............... 267 Classification of Allergens........ 267 Pathogenesis.............. 269 Immunological Stage of Allergic Reactions and Their Classification 269 The Pathochemical Stage of Allergic Reactions..... 274 Pathophysiological Stage of Allergic Reactions.... 276 Mechanisms of Formation of Allergic Reactions..... 277 Autoallergic Diseases........... 279 False Allergy (Paraallergy, Heteroallergy)..... 281 Prevention of the Allergy. Desensibilization...... 282 Chapter XIX. FEVER (MD, PhD, DSc, Professor Nikolay N. Zayko). 283 Etiology............... 283 Pathogenesis. The Role of the Thermoregulatory Centers in the Fever Development 284 Stages of the Fever............. 288 Types of Temperature Curves........... 289 Difference between Fever and Hyperthermia...... 291 Effect of Fever on Body Organs and Systems..... 292 Significance of Fever for Organism....... 293 Chapter XX. TUMORS (NEOPLASMS) (MD, PhD, DSc, Professor Vladislav A. Horban)..... 295 Experimental Models of Neoplasia......... 295 Features of the Neoplastic Tissue........ 296 Malignancy of Tumors............ 298 Etiology of Tumor............ 299 Pathogenesis of Tumor........... 302 The Tumor Effect on the Organism......... 309 The Role of the Organism in the Neoplastic Process... 310 Chapter XXI. STARVATION (MD, PhD, DSc, Professor Liudmila Ya. Danilova) 313 The Complete Starvation............ 313 Incomplete Starvation........... 318 Partial Starvation........... 319 Chapter XXII. HYPOXIA (MD, PhD, Associate Professor Natalia K. Simeonova) 321 Etiology............... 321 Pathogenesis.............. 322 Compensatory and Adaptive Reactions......... 322 Immediate Compensatory Reactions......... 323 Delayed Compensatory Reactions........ 324 Adaptation............. 326 Pathological Changes During the Hypoxia........ 326 Part Four PATHOPHYSIOLOGY OF ORGANS AND SYSTEMS Chapter XXIII. PATHOPHYSIOLOGY OF THE BLOOD SYSTEM (MD, PhD, Associate Professor Irina I. Pototskaya)... 329 Total Blood Volume Disorders.......... 329 Hemorrhage............. 331 Pathology of the Erythrocytes......... 332 Erythrocytosis............ 334 Anemia.............. 335 The Posthemorrhagic Anemia......... 336 Hemolytic Anemia............. 337 The Dyserythropoietic Anemia.......... 341 Pathological Changes of the Leukocytes...... 347 Disorders of the Leukopoiesis......... 347 Quantitative Changes of the Leukocytes in the Blood.. 347 The Qualitative Changes of the Leukocytes in the Blood.. 351 Hemoblastosis, Leukemia......... 354 Pathology of the Hemostasis........... 358 Hemorrhagic Syndromes........... 359 Thrombotic Syndromes............ 363 Chapter ХХIV. Pathophysiology of cardiovascular disorders CAUSED BY HEART DYSFUNCTION (MD, PhD, DSc, Professor Gennadiy M. Butenko)..... 367 Heart Failure............. 368 Heart Failure Associated with Volume Overload. Mechanisms of Compensation 369 Heart Failure due to Myocardium Damage...... 377 Cardiac Rhythm Disorders........... 383 Chapter XXV. Pathophysiology of cardiovascular disorders CAUSED BY VESSELS DYSFUNCTION (MD, PhD, DSc, Professor Yuriy V. Byts; MD, PhD, DSc, Professor Nikolay V. Krishtal) 390 Pathological Changes in the Vessels of the Compensatory Type. Atherosclerosis 392 Experimental Models of the Atherosclerosis..... 393 Etiology............... 393 Pathogenesis.............. 399 Pathophysiology of Vessels of the Resistance (Muscle) Type. 403 Arterial Hypertension........... 403 Experimental models of the hypertension..... 404 Etiology............... 406 Pathogenesis.............. 407 Pulmonary Hypertension.......... 414 Arterial Hypotension............ 415 Chapter XXVI. PATHOPHYSIOLOGY OF EXTREME STATES (MD, PhD, Associate Professor Larisa P. Zayarnaya)... 417 Shock............... 417 Etiology............... 417 Pathogenesis.............. 418 Specific Features of the Shock Development..... 428 Collapse............... 435 Chapter XXVII. PATHOPHYSIOLOGY OF THE RESPIRATION (MD, PhD, DSc, Professor Vladimir A. Mikhnev)..... 440 Disorders of the Alveolar Ventilation....... 440 Disregulative Ventilative Respiratory Insufficiency.. 441 Obstructive Ventilative Insufficiency....... 446 Restrictive Ventilative Insufficiency....... 448 Disorders of the Respiration in the Pulmonary Obstructive and Restrictive Processes.............. 451 Diffusive Insufficiency of the Lungs........ 451 Decrease of the Total Blood Flow in the Lungs..... 454 Breaking of the Total and Local Ventilation-Perfusion Ratio in the Lungs 454 Impact of the Respiratory Failure on the Body..... 456 Disorders of Non-Respiratory Functions of the Lungs..... 459 Chapter XXVIII. PATHOPHYSIOLOGY OF THE DIGESTIVE SYSTEM (MD, PhD, DSc, Professor Oleg I. Sukmanskiy; MD, PhD, DSc, Professor Vitaliy A. Kostenko)...... 461 Appetite Disorder............ 461 Digestive Disorders in the Oral Cavity...... 463 The Chewing Disorder............ 463 Dental Caries............. 463 Periodontal Pathology........... 465 Disorders of Salivation......... 466 Disorders of Swallowing and Esophageal Motility...... 468 Digestive Disorders in the Stomach....... 469 Disorders of the Stomach Secretion....... 469 Disorders of the Stomach Motility........ 471 Peptic Ulcer.............. 475 Intestinal Digestive Disorders........ 478 Digestive Disorders Connected with Impairment of the Bile and Pancreatic Juice Secretion... 478 Pancreatitis.............. 479 Disorders of the Parietal Digestion...... 481 Disorder of Intestinal Absorption. Malabsorption Syndrome. 483 Intestinal Motility Disorders......... 484 Intestinal Obstruction.......... 485 Intestinal Dysbiosis. Intestinal Autointoxication.... 486 Disorders of Hormone Synthesis in the Digestive System.. 487 Chapter XXIX. PATHOPHYSIOLOGY OF THE LIVER (MD, PhD, Associate Professor Irina I. Pototskaya)... 490 General Characteristics of Pathological Processes in the Liver 490 Hepatic Insufficiency........... 491 Disorders of the Metabolism in Liver........ 493 Hepatic Protective Dysfunctions....... 496 Hepatic Coma.............. 497 Disorders of the Cholopoiesis and Cholekinesis.... 499 Disorders of the Hemodynamics at Deseases of Liver... 506 Chapter XXX. PATHoPHYSIOLOGY OF THE KIDNEYS (MD, PhD, DSc, Professor Nikolay V. Krishtal; MD, PhD, DSc, Professor Anatoliy I. Gozhenko) 508 Disorders of the Renal Functions and Processes.... 508 Disorders of Glomerular Filtration....... 509 Disorders of Tubular Reabsorption and Secretion... 511 Pathogenesis of the Renal Syndromes......... 515 Nephrotic Syndrome........... 517 Acute Renal Failure.......... 518 Chronic Renal Failure........... 520 Tubulointerstitial Syndrome........ 521 Etiology and Pathogenesis of the Main Renal Diseases.... 522 Glomerulonephritis........... 522 Pyelonephritis............ 525 Chapter XXXI. PATHOPHYSIOLOGY OF THE ENDOCRINE SYSTEM (MD, PhD, DSc, Professor Aleksandr G. Reznikov)... 527 Hormones and Their Role in the Body......... 527 Etiology and Pathogenesis of Endocrine Disorders..... 530 Dysfunction of the Hypothalamic-Pituitary System..... 538 Dysfunctions of the Pituitary......... 538 Neuroendocrine Diseases......... 541 Disorders of Other Endocrine Organs......... 542 Dysfunctions of the Thyroid Gland........ 542 Dysfunctions of the Parathyroid Glands...... 546 Dysfunctions of the Adrenal Glands....... 547 Dysfunctions of the Sex Glands........ 550 The Endocrine Dysfunction of the Thymus..... 552 Dysfunctions of the Pineal Body (Epiphysis).... 552 Stress and General Adaptation Syndrome...... 553 Diabetes Mellitus (MD, PhD, DSc, Professor Nikolay V. Krishtal) 554 Type 1 Diabetes Mellitus........... 557 Type 2 Diabetes Mellitus........... 562 Chapter ХХХII. PATHOPHYSIOLOGY OF THE NERVOUS SYSTEM (MD, PhD, DSc, Professor Vladimir A. Mikhnev)..... 566 Etiology and Pathogenesis of the Nervous System Disorders.. 566 Dysfunctions of the Nervous System....... 569 Dysfunctions of the Nerve Cells and Conductors.... 569 Dysfunctions of the Synapses.......... 571 Disorders of the Sensitivity.......... 573 Pain................ 575 Disorders of the Motor Functions of the Nervous System.. 580 The Nervous Trophicity and Dystrophic Process..... 586 Dysfunctions of the Autonomic Nervous System...... 589 Experimental Models of Emotional Reactions and their Disorders 591 Coma (MD, PhD, Associate Professor Larisa P. Zayarnaya).... 595 References............. 603 Index 638
Дод.точки доступу:
Krishtal, Nikolay Vasylovych
Кришталь Микола Васильович
Mikhnev, Volodymyr Anatoliyovych
Міхньов Володимир Анатолійович
Zaykо, Nikolay Nykyforovych
Зайко Микола Никифорович
Byts, Y. V.
Butenko, G. M.
Reznikov, O. G.
Danylova, L. Ya.
Pototska, I. I.
Horban, V. O.
Simeonova, N. K.
Kostenko, V. O.
Костенко Віталій Олександрович та ін.
Krishtal, Nikolay Vasylovych \ed.\
Mikhnev, Volodymyr Anatoliyovych \ed.\

Примірників всього: 80
ЧЗ (1), Наук.Аб. (3), Гурт.4 (1), Уч.Аб. (75)
Вільні: ЧЗ (1), Наук.Аб. (3), Гурт.4 (1), Уч.Аб. (75)

Найти похожие

   616-092
   П 20


    Pathophysiology : textbook [for students of higher medical education establishments] / ed. N. V. Krishtal, V. A. Mikhnev ; N. V. Krishtal, V. A. Mikhnev, N. N. Zayko et al. - K. : Medicine Publishing, 2017. - 655 p. : il. - На англ. мові. - References: p. 603-637. - Index: p. 638-655. - ISBN 978-617-505-616-5 : 610.00 грн
Переклад назви: Патофізіологія: підручник / за ред. М. В. Кришталя, В. А. Міхньова

УДК

616-092(075.8)

Рубрики: ПАТОФІЗІОЛОГІЯ(англ)--Підручник

Кл.слова (ненормовані):
підручники -- national textbook
Анотація: The textbook is prepared by a team of staff at higher educational institutions and academic research institutions of Ukraine, who are recognized experts in various aspects of pathophysiology that gives reason this basic textbook to be national. It is recommended for English-speaking students of higher medical educational establishments. The textbook can be useful for teachers and physicians of all specialties. Abbreviations........................ 11 Preface........................... 14 Introduction (MD, PhD, DSc, Professor Nikolay N. Zayko).......15 The Subject and Tasks of Pathological Physiology............ 15 Relationship Between Pathological Physiology and Other Medical Sciences, Its Importance for Clinical Disciplines................ 15 Experiment as the Basic Method of Pathological Physiology........ 16 Historical Sketch of the Development of Pathological Physiology (MD, PhD, DSc, Professor Valentin F. Myslitskiy; MD, PhD, DSc, Professor Sergey V. Ziablitsev)...18 Part One GENERAL NOSOLOGY Chapter I. GENERAL THEORY OF DISEASES (MD, PhD, DSc, Professor Nikolay N. Zayko).............. 23 Health............................. 23 Disease............................. 24 Principles of Diseases Classification................. 25 Pathological Reaction, Pathological Process, Pathological Condition......26 Typical Pathological Processes......... 27 Main Periods (Stages) of Disease Development....... 27 Chapter II. ETIOLOGY AND PATHOGENESIS (MD, PhD, DSc, Professor Nikolay N. Zayko)..... 31 Etiology................... 31 Conditions of the Disease Occurrence...... 33 Pathogenesis................. 34 The Cause-and-Effect Relationship......... 35 General and Local.............. 36 Structure and Function............. 36 Nonspecific and Specific............ 36 Adaptation and Compensation.......... 37 Reactivity and its Role in Pathology (MD, PhD, DSc, Professor Liudmila Ya. Danilova) 38 Types of Resistance. Relations with Reactivity..... 39 Chapter III. PATHOGENIC EFFECT OF ENVIRONMENTAL FACTORS ON THE ORGANISM (MD, PhD, Associate Professor Natalia K. Simeonova) 41 Mechanical Trauma............. 41 Thermal Trauma............. 41 Barotrauma.............. 45 Radiation Injury.............. 46 Etiology............. 46 Pathogenesis............ 47 Acute Radiation Disease.......... 53 Chronic Radiation Disease........... 54 Electrotrauma.............. 55 Pathogenic Effect of Space Flight Factors....... 56 Chapter IV. THE ROLE OF HEREDITY, CONSTITUTION AND AGE IN PATHOLOGY (MD, PhD, Associate Professor Natalia K. Simeonova)....... 57 Genetically Determined Diseases........ 57 Classification............. 57 Etiology............. 58 Pathogenesis............ 59 Molecular Genetic (Hereditary) Diseases...... 60 Chromosomal Diseases.......... 65 Hereditary Predisposition........... 66 Genetic Examination of a Patient....... 66 Principles of Prevention and Treatment of Hereditary Diseases 69 Role of The Constitution in Pathology........ 70 Pathological Physiology of Fetal Development (MD, PhD, DSc, Professor Larisa A. Popova)...... 73 Ageing (MD, PhD, DSc, Professor Gennadiy M. Butenko)..... 74 Changes in the Body during Aging....... 77 Ageing and Diseases........... 82 Causes and Mechanisms of Ageing........ 83 The Ways of Influence on Ageing........ 84 Part Two GENERAL PATHOPHYSIOLOGY OF CELLS. TYPICAL METABOLIC DISORDERS Chapter V. PATHOPHYSIOLOGY OF CELL (MD, PhD, DSc, Professor Gennadiy M. Butenko)...... 86 Disturbances of Cells Functions........ 86 Disorders of Metabolic Processes and Environment Interaction... 87 Disturbance of Cell Energy Supply......... 88 Disturbances of Genetic Information Storage and Transfer. 89 Intracellular Synthesis Disorders......... 91 Dissimilation Interruption.......... 92 Cell Damage and Death............ 93 Chapter VI. PATHOLOGY OF ENERGY BALANCE (MD, PhD, DSc, Professor Liudmila Ya. Danilova; MD, PhD, DSc, Professor Nikolay V. Krishtal)..... 95 Chapter VII. PATHOPHYSIOLOGY OF CARBOHYDRATE METABOLISM (MD, PhD, DSc, Professor Liudmila Ya. Danilova; MD, PhD, DSc, Professor Nikolay V. Krishtal).... 98 Carbohydrate Metabolism and its Regulation...... 98 Pathology of the Carbohydrate Metabolism....... 100 Chapter VIII. Pathophysiology OF lipid METABOLISM (MD, PhD, DSc, Professor Nikolay V. Krishtal; MD, PhD, DSc, Professor Liudmila Ya. Danilova)... 105 Malabsorption of Lipids............ 105 Disorders of Lipid Transport and Deposition....... 105 Lipid Infiltration and Lipid Dystrophy...... 107 Disorder of Intermediate Lipid Metabolism...... 107 Disorders of Lipid Metabolism in The Adipose Tissue..... 108 Obesity................ 109 Weight Loss............... 114 Lipidoses.............. 115 Chapter IX. PATHOPHYSIOLOGY OF PROTEIN METABOLISM (MD, PhD, DSc, Professor Larisa A. Popova; MD, PhD, DSc, Professor Victor Ye. Dosenko).... 116 Disorders of Amino Acid Metabolism....... 116 Hereditary Disorders of Metabolism of Certain Amino Acids.. 117 Disorders of Final Stages of Protein Metabolism...... 119 Disorders of Proteins of the Blood....... 120 Disorders of the Nucleic Acids Metabolism...... 120 Chapter X. PATOPHYSIOLOGY OF ACID-BASE HOMEOSTASIS (MD, PhD, DSc, Professor Nikolay V. Krishtal)..... 122 Etiology, Pathogenesis and Forms of Acid-Base Imbalance.... 124 The Relationship between ABH and Mineral Exchange.... 124 Etiology and Classification of Non-Respiratory Acid-Base Imbalance 126 Pathological Effects of Acid-Base Imbalance on the Body.... 127 Mechanisms of Compensation of Acid-Base Imbalance.... 128 Chapter XI. PATOPHYSIOLOGY OF WATER-ELECTROLYTE BALANCE (MD, PhD, DSc, Professor Nikolay V. Krishtal; MD, PhD, DSc, Professor Oleg I. Sukmanskiy).... 132 Types, Causes, and Consequences of Water-Electrolyte Imbalance 136 Electrolyte Imbalance........... 142 The Exchange of Sodium and Its Imbalance....... 142 The Exchange of Potassium and Its Imbalance.... 143 The Exchange of Magnesium and Its Imbalance.... 144 The Exchange of Chlorine and Its Imbalance..... 145 The Exchange of Calcium and Its Imbalance...... 146 The Exchange of Phosphorus and Its Imbalance...... 148 The Osteoporosis............. 149 Chapter XII. PATHOPHYSIOLOGY OF MICROELEMENTS METABOLISM (MD, PhD, DSc, Professor Nikolay V. Krishtal)..... 151 Iron Exchange and Imbalance........... 152 Copper Exchange and Imbalance......... 156 Zinc Exchange and Imbalance........... 159 Manganese Exchange And Imbalance......... 161 Chromium Exchange and Imbalance.......... 162 Vanadium Exchange and Imbalance.......... 163 Molybdenum Exchange and Imbalance........ 165 Selenium Exchange and Imbalance.......... 165 Iodine Exchange And Imbalance......... 169 Fluoride Exchange and Imbalance.......... 171 Chapter XIII. PATHOPHYSIOLOGY OF VITAMINS METABOLISM (MD, PhD, DSc, Professor Nikolay V. Krishtal)..... 173 Classification and General Characteristics of Vitamins in the Human Body 173 Sources of Vitamins and Their Metabolism in the Body.... 177 Main Causes of Vitamin Deficiency Development..... 179 Deficiency of Antineurotic Vitamin В1........ 181 Deficiency of Riboflavin........... 182 Deficiency of Antipellagric Vitamin РР...... 182 Deficiency of Antidermatitic Vitamin В6...... 183 Deficiency of Folic Acid........... 184 Deficiency of Antianemic Vitamin В12...... 185 Deficiency of Antiscorbutic Vitamin C....... 186 Deficiency of Biotin............ 187 Deficiency of Rutin.......... 188 Deficiency of Antixerophthalmic Vitamin A...... 188 Deficiency of Antirachitic Vitamin D........ 188 Deficiency of Vitamin E......... 190 Deficiency of Vitamin F......... 191 Deficiency of Antihemorrhagic Vitamin K..... 192 Hypervitaminoses............. 192 Part Three TYPICAL PATHOLOGICAL PROCESSES Chapter XIV. Pathophysiology of peripheral blood CIRCULATION (MD, PhD, DSc, Professor Yuriy V. Byts; MD, PhD, DSc, Professor Anatoliy V. Kubyshkin).... 194 Arterial Hyperemia........... 196 Venous Hyperemia............. 201 Ischemia............... 202 Stasis.............. 206 Thrombosis............. 206 Embolism............... 209 Chapter XV. microcirculatory disorders (MD, PhD, DSc, Professor Yuriy V. Byts; MD, PhD, DSc, Professor Anatoliy V. Kubyshkin) 213 Intravascular Mechanisms of Microcirculatory Disorders.. 214 Extravascular Mechanisms of Microcirculatory Disorders.. 217 Chapter XVI. INFLAMMATION (MD, PhD, DSc, Professor Nikolay V. Krishtal) 218 Experimental Models of Inflammation......... 219 Etiology of Inflammation........... 220 Pathogenesis of Inflammation.......... 220 Alteration............. 221 The Inflammatory Cells and Mediators........ 225 The Influence of Inflammatory Mediators on the Organism. 233 Vascular Reactions in Inflammation....... 234 Exudation.............. 236 Emigration of the White Blood Cells...... 237 Phagocytosis.............. 242 Proliferation and Regeneration........ 244 Classification............ 249 Chapter XVII. PATHOPHYSIOLOGY OF THE IMMUNITY (MD, PhD, DSc, Professor Vladislav A. Horban; MD, PhD, DSc, Professor Nikolay V. Krishtal) 251 The Main Functions and Structure of the Immune System... 251 Genesis and Function of T- and B-Lymphocytes...... 253 Experimental Models of Hypofunction of the Immune System... 257 Immune Deficiency Diseases......... 257 Immune-Suppressive Diseases........ 263 Disorders of the Systems that Functionally Associated with the Immune System 264 Chapter XVIII. ALLERGY (MD, PhD, DSc, Professor Vladislav A. Horban) 267 Etiology............... 267 Classification of Allergens........ 267 Pathogenesis.............. 269 Immunological Stage of Allergic Reactions and Their Classification 269 The Pathochemical Stage of Allergic Reactions..... 274 Pathophysiological Stage of Allergic Reactions.... 276 Mechanisms of Formation of Allergic Reactions..... 277 Autoallergic Diseases........... 279 False Allergy (Paraallergy, Heteroallergy)..... 281 Prevention of the Allergy. Desensibilization...... 282 Chapter XIX. FEVER (MD, PhD, DSc, Professor Nikolay N. Zayko). 283 Etiology............... 283 Pathogenesis. The Role of the Thermoregulatory Centers in the Fever Development 284 Stages of the Fever............. 288 Types of Temperature Curves........... 289 Difference between Fever and Hyperthermia...... 291 Effect of Fever on Body Organs and Systems..... 292 Significance of Fever for Organism....... 293 Chapter XX. TUMORS (NEOPLASMS) (MD, PhD, DSc, Professor Vladislav A. Horban)..... 295 Experimental Models of Neoplasia......... 295 Features of the Neoplastic Tissue........ 296 Malignancy of Tumors............ 298 Etiology of Tumor............ 299 Pathogenesis of Tumor........... 302 The Tumor Effect on the Organism......... 309 The Role of the Organism in the Neoplastic Process... 310 Chapter XXI. STARVATION (MD, PhD, DSc, Professor Liudmila Ya. Danilova) 313 The Complete Starvation............ 313 Incomplete Starvation........... 318 Partial Starvation........... 319 Chapter XXII. HYPOXIA (MD, PhD, Associate Professor Natalia K. Simeonova) 321 Etiology............... 321 Pathogenesis.............. 322 Compensatory and Adaptive Reactions......... 322 Immediate Compensatory Reactions......... 323 Delayed Compensatory Reactions........ 324 Adaptation............. 326 Pathological Changes During the Hypoxia........ 326 Part Four PATHOPHYSIOLOGY OF ORGANS AND SYSTEMS Chapter XXIII. PATHOPHYSIOLOGY OF THE BLOOD SYSTEM (MD, PhD, Associate Professor Irina I. Pototskaya)... 329 Total Blood Volume Disorders.......... 329 Hemorrhage............. 331 Pathology of the Erythrocytes......... 332 Erythrocytosis............ 334 Anemia.............. 335 The Posthemorrhagic Anemia......... 336 Hemolytic Anemia............. 337 The Dyserythropoietic Anemia.......... 341 Pathological Changes of the Leukocytes...... 347 Disorders of the Leukopoiesis......... 347 Quantitative Changes of the Leukocytes in the Blood.. 347 The Qualitative Changes of the Leukocytes in the Blood.. 351 Hemoblastosis, Leukemia......... 354 Pathology of the Hemostasis........... 358 Hemorrhagic Syndromes........... 359 Thrombotic Syndromes............ 363 Chapter ХХIV. Pathophysiology of cardiovascular disorders CAUSED BY HEART DYSFUNCTION (MD, PhD, DSc, Professor Gennadiy M. Butenko)..... 367 Heart Failure............. 368 Heart Failure Associated with Volume Overload. Mechanisms of Compensation 369 Heart Failure due to Myocardium Damage...... 377 Cardiac Rhythm Disorders........... 383 Chapter XXV. Pathophysiology of cardiovascular disorders CAUSED BY VESSELS DYSFUNCTION (MD, PhD, DSc, Professor Yuriy V. Byts; MD, PhD, DSc, Professor Nikolay V. Krishtal) 390 Pathological Changes in the Vessels of the Compensatory Type. Atherosclerosis 392 Experimental Models of the Atherosclerosis..... 393 Etiology............... 393 Pathogenesis.............. 399 Pathophysiology of Vessels of the Resistance (Muscle) Type. 403 Arterial Hypertension........... 403 Experimental models of the hypertension..... 404 Etiology............... 406 Pathogenesis.............. 407 Pulmonary Hypertension.......... 414 Arterial Hypotension............ 415 Chapter XXVI. PATHOPHYSIOLOGY OF EXTREME STATES (MD, PhD, Associate Professor Larisa P. Zayarnaya)... 417 Shock............... 417 Etiology............... 417 Pathogenesis.............. 418 Specific Features of the Shock Development..... 428 Collapse............... 435 Chapter XXVII. PATHOPHYSIOLOGY OF THE RESPIRATION (MD, PhD, DSc, Professor Vladimir A. Mikhnev)..... 440 Disorders of the Alveolar Ventilation....... 440 Disregulative Ventilative Respiratory Insufficiency.. 441 Obstructive Ventilative Insufficiency....... 446 Restrictive Ventilative Insufficiency....... 448 Disorders of the Respiration in the Pulmonary Obstructive and Restrictive Processes.............. 451 Diffusive Insufficiency of the Lungs........ 451 Decrease of the Total Blood Flow in the Lungs..... 454 Breaking of the Total and Local Ventilation-Perfusion Ratio in the Lungs 454 Impact of the Respiratory Failure on the Body..... 456 Disorders of Non-Respiratory Functions of the Lungs..... 459 Chapter XXVIII. PATHOPHYSIOLOGY OF THE DIGESTIVE SYSTEM (MD, PhD, DSc, Professor Oleg I. Sukmanskiy; MD, PhD, DSc, Professor Vitaliy A. Kostenko)...... 461 Appetite Disorder............ 461 Digestive Disorders in the Oral Cavity...... 463 The Chewing Disorder............ 463 Dental Caries............. 463 Periodontal Pathology........... 465 Disorders of Salivation......... 466 Disorders of Swallowing and Esophageal Motility...... 468 Digestive Disorders in the Stomach....... 469 Disorders of the Stomach Secretion....... 469 Disorders of the Stomach Motility........ 471 Peptic Ulcer.............. 475 Intestinal Digestive Disorders........ 478 Digestive Disorders Connected with Impairment of the Bile and Pancreatic Juice Secretion... 478 Pancreatitis.............. 479 Disorders of the Parietal Digestion...... 481 Disorder of Intestinal Absorption. Malabsorption Syndrome. 483 Intestinal Motility Disorders......... 484 Intestinal Obstruction.......... 485 Intestinal Dysbiosis. Intestinal Autointoxication.... 486 Disorders of Hormone Synthesis in the Digestive System.. 487 Chapter XXIX. PATHOPHYSIOLOGY OF THE LIVER (MD, PhD, Associate Professor Irina I. Pototskaya)... 490 General Characteristics of Pathological Processes in the Liver 490 Hepatic Insufficiency........... 491 Disorders of the Metabolism in Liver........ 493 Hepatic Protective Dysfunctions....... 496 Hepatic Coma.............. 497 Disorders of the Cholopoiesis and Cholekinesis.... 499 Disorders of the Hemodynamics at Deseases of Liver... 506 Chapter XXX. PATHoPHYSIOLOGY OF THE KIDNEYS (MD, PhD, DSc, Professor Nikolay V. Krishtal; MD, PhD, DSc, Professor Anatoliy I. Gozhenko) 508 Disorders of the Renal Functions and Processes.... 508 Disorders of Glomerular Filtration....... 509 Disorders of Tubular Reabsorption and Secretion... 511 Pathogenesis of the Renal Syndromes......... 515 Nephrotic Syndrome........... 517 Acute Renal Failure.......... 518 Chronic Renal Failure........... 520 Tubulointerstitial Syndrome........ 521 Etiology and Pathogenesis of the Main Renal Diseases.... 522 Glomerulonephritis........... 522 Pyelonephritis............ 525 Chapter XXXI. PATHOPHYSIOLOGY OF THE ENDOCRINE SYSTEM (MD, PhD, DSc, Professor Aleksandr G. Reznikov)... 527 Hormones and Their Role in the Body......... 527 Etiology and Pathogenesis of Endocrine Disorders..... 530 Dysfunction of the Hypothalamic-Pituitary System..... 538 Dysfunctions of the Pituitary......... 538 Neuroendocrine Diseases......... 541 Disorders of Other Endocrine Organs......... 542 Dysfunctions of the Thyroid Gland........ 542 Dysfunctions of the Parathyroid Glands...... 546 Dysfunctions of the Adrenal Glands....... 547 Dysfunctions of the Sex Glands........ 550 The Endocrine Dysfunction of the Thymus..... 552 Dysfunctions of the Pineal Body (Epiphysis).... 552 Stress and General Adaptation Syndrome...... 553 Diabetes Mellitus (MD, PhD, DSc, Professor Nikolay V. Krishtal) 554 Type 1 Diabetes Mellitus........... 557 Type 2 Diabetes Mellitus........... 562 Chapter ХХХII. PATHOPHYSIOLOGY OF THE NERVOUS SYSTEM (MD, PhD, DSc, Professor Vladimir A. Mikhnev)..... 566 Etiology and Pathogenesis of the Nervous System Disorders.. 566 Dysfunctions of the Nervous System....... 569 Dysfunctions of the Nerve Cells and Conductors.... 569 Dysfunctions of the Synapses.......... 571 Disorders of the Sensitivity.......... 573 Pain................ 575 Disorders of the Motor Functions of the Nervous System.. 580 The Nervous Trophicity and Dystrophic Process..... 586 Dysfunctions of the Autonomic Nervous System...... 589 Experimental Models of Emotional Reactions and their Disorders 591 Coma (MD, PhD, Associate Professor Larisa P. Zayarnaya).... 595 References............. 603 Index 638
Дод.точки доступу:
Krishtal, Nikolay Vasylovych
Кришталь Микола Васильович
Mikhnev, Volodymyr Anatoliyovych
Міхньов Володимир Анатолійович
Zaykо, Nikolay Nykyforovych
Зайко Микола Никифорович
Byts, Y. V.
Butenko, G. M.
Reznikov, O. G.
Danylova, L. Ya.
Pototska, I. I.
Horban, V. O.
Simeonova, N. K.
Kostenko, V. O.
Костенко Віталій Олександрович та ін.
Krishtal, Nikolay Vasylovych \ed.\
Mikhnev, Volodymyr Anatoliyovych \ed.\

Примірників всього: 99
Наук.Аб. (6), Гурт.4 (1), Уч.Аб. (92)
Вільні: Наук.Аб. (6), Гурт.4 (1), Уч.Аб. (92)

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   616.1/9
   С 37


    Family Medicine. In 3 books : textbook [for students of higher education establishments - medical universities, institutes and academies]. Book 2. Symptoms and syndromes in clinical course of internal diseases / ed. O. M. Hyrina, L. M. Pasiyeshvili ; L. S. Babinets, O. M. Barna, S. V. Biletskyi et al. - K. : Medicine Publishing, 2018. - 375 p. : il. - На англ. мові. - ISBN 978-617-505-493-2. - ISBN 978-617-505-652-3 (Вооk 2) : 410.00 грн
Переклад назви: Сімейна медицина. В 3-х кн. Кн. 2. Синдроми і симптоми у клініці внутрішніх хвороб: підручник / за ред. О. М. Гиріної, Л. М. Пасієшвілі

ДРНТІ	76
УДК	616.1/9:614.254.3(075.8)

Рубрики: ТЕРАПІЯ(англ)--Підручник

СІМЕЙНА ПРАКТИКА(англ)--Підручник

Кл.слова (ненормовані):
підручники -- national textbook
Анотація: The textbook is composed in accordance with curriculum in the specialty “General Practice — Family Medicine”. The textbook presents the current approach to common problems in family physician practice, highlights the main symptoms and syndromes in cardiology, gastroenterology, pulmonology, nephrology, hematology, endocrinology as well as other syndromes that general practitionerfamily physician most often manages in medical practical activity. Information on the causes, pathogenesis, clinical manifestations, diagnostic search algorithms in the presence of these syndromes, differential diagnosis of various diseases manifested by these symptoms and syndromes is provided in the textbook. Assessment and treatment algorithms, first aid managing and practical recommendations are proposed in detail. For students of higher education establishments — medical universities, institutes and academies, internship doctors in the specialty “General Practice — Family Medicine”. Chapter 1. Syndromes in Cardiology............. 5 Chest Pain Syndrome (S.V. Biletskyi)............. 5 Edematous Syndrome (S.V. Biletskyi)........... 29 Syndrome of Arterial Hypotonia (A.A. Zazdravnov)....... 32 Sick Sinus Syndrome (A.A. Zazdravnov)........... 37 Syndrome of Premature Ventricular Excitation (S.V. Biletskyi).. 40 Long Q—T Interval Syndrome (S.V. Biletskyi)......... 44 Syndrome of Chronic Heart Failure (O.V. Syniachenko)...... 47 Chapter 2. Syndromes in Gastroenterology (V.M. Chernobrovyi). 59 Abdominal Pain Syndrome............... 59 Dyspepsia...................... 64 Heartburn....................... 67 Dysphagia...................... 70 Nausea and Vomiting.................. 72 Constipation....................... 75 Chronic Diarrhea................... 77 Jaundice....................... 80 Portal Hypertension.................. 83 Chapter 3. Syndromes in Pulmonology (L.S. Babinets, I.O. Borovyk)...87 Syndrome of Pulmonary Tissue Consolidation.......... 87 Syndrome of Bronchial Obstruction............ 101 Syndrome of Pulmonary Insufficiency............ 108 Syndrome of Fluid Accumulation in the Pleural Space..... 116 Syndrome of Air in the Pleural Space............. 126 Syndrome of Cavity in the Lung Tissue............. 131 Syndrome of Increased Airiness of the Lungs (Emphysema).... 135 Syndrome of Obstructive Atelectasis.............. 139 Syndrome of Compressive Atelectasis............ 141 Syndrome of Pulmonary Arterial Hypertension......... 141 Syndrome of Cough................... 145 Chapter 4. Syndromes in Nephrology............. 158 Urinary Syndrome (V.M. Lisovyi).............. 158 Nephrotic Syndrome (N.M. Zhelezniakova)......... 175 Chapter 5. Syndromes in Hematology........... 185 Anemia Syndrome (T.M. Pasiyeshvili)............ 185 Lymphadenopathy Syndrome (L.M. Pasiyeshvili)....... 192 Chapter 6. Syndromes in Rheumatology (L.M. Pasiyeshvili, O.M. Barna)...204 Articular Syndrome................... 204 Osteoporotic Syndrome.................. 213 Chapter 7. Syndromes in Endocrinology........... 231 Hyperglycemic Syndrome (T.M. Pasiyeshvili).......... 231 Metabolic Syndrome (S.V. Biletskyi).............. 236 Chapter 8. Syndromes in Pediatry.............. 241 Anemia Syndrome (T.V. Frolova)............. 241 Lymphadenopathy Syndrome (I.I. Tereshchenkova)....... 250 Apnea Syndrome (V.I. Velychko, H.O. Danylchuk)....... 254 Foreign Bodies in the Airway, Ear and Esophagus (V.I. Velychko, H.O. Danylchuk)...263 Syndrome of Neck and Back Pain in Children (V.I. Velychko, H.O. Danylchuk).....273 Syndrome of Sex Development Disorders (V.I. Velychko, H.O. Danylchuk).....281 Traumas. Traumatic External and Internal Hemorrhages (V.I. Velychko, H.O. Danylchuk)...297 Gastrointestinal Hemorrhages (V.I. Velychko, H.O. Danylchuk)... 310 Chapter 9. Other Syndromes in Medical Practice....... 319 Hepatomegaly Syndrome (L.M. Pasiyeshvili, L.M. Bobro)...... 319 Splenomegaly Syndrome (L.M. Bobro, L.M. Pasiyeshvili).... 328 Hepatolienal Syndrome (L.M. Pasiyeshvili, L.M. Bobro)....... 336 Subfebrile Condition in Adults (N.M. Zhelezniakova)........ 340 Skin Itch (N.D. Chukhriienko)................. 350 Dyspnea Syndrome (Ye.Ya. Skliarov).............. 360 Chronic Fatigue Syndrome (V.M. Zhdan, L.M. Shylkina, Yu.M. Kazakov)...364 Myeloproliferative syndrome...................... 169 Syndrome of blood coagulation disorders ................. 169 Iron deficiency anemia....................... 172 Megaloblastic anemia........................ 174 Hemolytic anemias..........................177 Hereditary spherocytic anemia................. 180 Glucose-6-phosphate dehydrogenase (G-6-PD) deficiency anemia... 181 Thalassemias ....................... 183 Sickle cell anemia...................... 186 Hemoblastosis........................... 188 Acute myeloblastic leukemia................. 188 Chronic myelocytic leukemia................. 191 Polycythemia vera..................... 193 Acute lymphoblastic leukemia.................. 194 Chronic lymphocytic leukemia ................. 196 Hemophilia............................. 198 Idiopathic thrombocytopenic purpura (Werlhof's disease)..........200 Henoch-Schonlein syndrome......................202 CHAPTERS. ENDOCRINE SYSTEM..................203 Patology of the thyroid gland...................... 203 Hypothyroidism.......................203 Hyperthyroidism........................207 Diabetes mellitus..........................210 APPENDIX. PATIENT INQUIRY................... 222
Дод.точки доступу:
Babinets, L. S.
Бабінець Л. С.
Barna, Olha Mykolayivna
Барна Ольга Миколаївна
Biletskyi, S. V.
Білецький С. В.
Bobro, Liliia Mykolaivna
Бобро Лілія Миколаївна
Borovyk, Iryna Olehivna
Боровик Ірина Олегівна
Velychko, Valentyna Ivanivna
Величко Валентина Іванівна
Danylchuk, H. O.
Zhdan, V. M.
Ждан Вячеслав Миколайович
Zhelezniakova, N. M.
Железнякова Н. М.
Kazakov, Yu. M.
Казаков Ю. М.
Pasiyeshvili, Liudmyla Mykhailivna
Пасієшвілі Людмила Михайлівна
Skliarov, Ye. Ya.
Скляров Євген Якович
Chernobrovyi, V. M.
Чорнобривий В. М.
Chukhgriienko, N. D.
Чухрієнко Н. Д.
Shylkina L. M.
Шилкіна Людмила Миколаївна
Hyrina, Olha Mykolayivna \ed.\
Гиріна Ольга Миколаївна
Pasiyeshvili, Liudmyla Mykhailivna \ed.\

Примірників всього: 28
ЧЗ (1), Наук.Аб. (3), Гурт.4 (1), Уч.Аб. (23)
Вільні: ЧЗ (1), Наук.Аб. (3), Гурт.4 (1), Уч.Аб. (23)

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   616.9
   І-74


    Pediatric Infectious Diseases : [textbook for students of higher medical educational establishments of the IVth level of accreditation] / S. O. Kramarov [et al.] ; ed.: S. O. Kramarov, O. B. Nadraga. - 3rd ed. - К. : Медицина, 2016. - 238 p. : табл. - На англ. мові. - ISBN 978-617-505-490-1 : 160.00 грн
Переклад назви: Інфекційні хвороби у дітей: підручник для студентів вищих мед. навч. закладів IV рівня акредитації / за ред. С. Крамарьова, О. Надраги

ДРНТІ	76.29.50	76.29.47
УДК	616.9-053.2(075.8)

Рубрики: ИНФЕКЦИОННЫЕ БОЛЕЗНИ(АНГЛ)--Підручник

ДЕТИ(АНГЛ)

Кл.слова (ненормовані):
Педиатрия -- national textbook
Анотація: У підручнику представлено класичні і нові дані про інфекційні хвороби в дітей. Наведено сучасні відомості про етіологію, епідеміологію, патогенез, клінічну картину, методи діагностики та лікування найпоширениших інфекційних захворювань серед дітей в Україні. До кожної теми подано перелік питань і тестів для самоконтролю засвоєних знань. Для студентів і лікарів-інтернів вищих медичних навчальних закладів IV рівня акредитації. The textbook presents classical and new data on pediatric infectious diseases, contemporary information on etiology, pathogenesis, clinical presentation, and methods of diagnosis; treatments for the most widely spread infectious diseases of children in Ukraine. Every topic is followed by a list of questions and tests for self-control of acquired knowledge. For students and interns of higher medical education institutions of the IV level of accreditation Foreword Measles Rubella Varicella Mumps Infection Pertussis Diphtheria Streptococcal Infection Acute Respiratory Viral Infections Poliomyelitis Herpetic infection Cytomegaloviral Infection Infectious Mononucleosis Meningococcal Infection Purulent Meningitis Acute Intestinal Infections Yersinial Infection Viral Hepatitis HIV Infection Fundamentals of Vaccinal Prevention
Дод.точки доступу:
Kramarov, Serhiy Oleksandrovych
Крамарьов Сергій Олександрович
Nadraga, Oleksandr Bohdanovych
Надрага Олександр Богданович
Pypa, Larysa Volodymyrivna
Пипа Лариса Володимирівна
Kharchenko, Y. P.
Харченко Юрій Петрович
Lytvynenko, N. G.
Литвиненко Наталія Григорівна
Palatna, L. O.
Палатна Людмила Олександрівна
Shpak, I. V.
Шпак Ірина Володимирівна
Doroshenko, V. O.
Дорошенко Віталій Олександрович
Voronov, О.О.
Воронов Олександр Олександрович
Lysheniuk, S. A.
Лишенюк Світлана Адамівна
Shostakovych-Koretska, L. R.
Шостакович-Корецька Людмила Романівна
Chernyshova, L. I.
Kramarov, Serhiy Oleksandrovych \ed.\
Nadraga, Oleksandr Bohdanovych \ed.\

Примірників всього: 50
Наук.Аб. (3), Гурт.4 (1), Уч.Аб. (46)
Вільні: Наук.Аб. (3), Гурт.4 (1), Уч.Аб. (46)

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10.

   616.1/9
   С 37


    Family Medicine. In 3 books : [textbook for students of higher medical education establishments of the 4th level of accreditation]. Book 1. General Issues of Family Medicine / O. M. Hyrina, L. M. Pasiyeshvili, O. M. Barna et al.; ed. O. M. Hyrina, L. M. Pasiyeshvili. - K. : Medicine Publishing, 2016. - 558 p. : il. - На англ. мові. - ISBN 978-617-505-493-2. - ISBN 978-617-505-494-9 (Вооk 1) : 410.00 грн
Переклад назви: Сімейна медицина. В 3-х кн. Кн. 1. Загальні питання сімейної медицини: підручник для мед. ВНЗ ІV р.а. / за ред. О. М. Гиріної, Л. М. Пасієшвілі

ДРНТІ	76
УДК	616.1/9:614.254.3(075.8)

Рубрики: ТЕРАПІЯ(англ)--Підручник

СІМЕЙНА ПРАКТИКА(англ)--Підручник

Кл.слова (ненормовані):
підручники -- national textbook
Анотація: The book explores the theoretical basis of family medicine. It also seeks to ana-lyze the social preconditions of the need for family medicine, the main aspects of the family doctor's practice, the working process problems as well as the means to solve them. The book summarizes years of experience in teaching family medicine at lead-ing medical universities of Ukraine.The authors outline modern views in general practice and the concept of its devel-opment; describes the or¬ganization of outpatient care in the most widespread diseases of the therapeutic profile; study the methods of providing emergency assistance in life-threatening conditions. The textbook provides information on the diagno¬sis, treatment, prevention, prophylactic medical observation, examination of incapacity for work, which will allow the doctor to properly assess symptoms, determine a list of diseases for differential diagnosis, and in future — to formulate a diagnosis and plan treatment and rehabilitation activities. MAIN ABBREVIATIONSCHAPTER 1. The Place of Family Medicine in the General Structure of Public Health and the Principles of Family Public Service on the Basis of Family Medi-cine. The Organization of Family Doctor's Work. The Peculiarities of Out-of-Hospital Therapeutic Care1.1. The Key Aspects of Training and the Functions of a Family Doctor1.2. A Systemic Theoretical Basis of the Family1.3. The Psychogenic Aspects of Family Doctor's Work. Solving Social and Medical Problems of the FamilyCHAPTER 2. Insurance Medicine and Quality Standards for Family Medicine2.1. Family Medicine and Health Insurance in Ukraine2.2. Mandatory and Voluntary Health Insurance. Health Care Funding Options in Terms of Health InsuranceReferences2.3. Family Medicine Models. International ExperienceReferences2.4. The Role of Professional Organizations in Family Doctor's Practice. International ExperienceReferencesCHAPTER 3. Fundamentals of Informatics, Evidence Medicine, Screening Diagno-sis, Clinical Observation, Telemedicine3.1. Fundamentals of Informatics3.2. TelemedicineAdvanced and Experimental ServiceTelemedicine in Ukraine3.3. Evidence-Based Medicine3.4. Screening Diagnosis3.5. Clinical observationReferencesCHAPTER 4. Medical and Social Aspects of Public Health4.1. The Family Physician's Role in Promotion of Healthy Lifestyle, Prevention Examsand Preventive Care4.2. Health Promotion and Primary PreventionReferences4.3. Screening of Oncological DiseasesReferencesCHAPTER 5. Evaluation of Risk Factor Prevalence in the Development of Major Chronic Non-Communicable Diseases and Elaboration of Preventive Measures with Account for Syndrome-Based ApproachCHAPTER 6. Prevention of the Most Common Therapeutic Diseases6.1. Circulatory System Diseases AtherosclerosisIschemic Heart Disease (IHD)HypertensionCongestive heart failure6.2. Respiratory System DiseasesChronic Obstructive Pulmonary DiseaseBronchial Asthma6.3. Diseases of the EsophagusFunctional Diseases of the EsophagusGastroesophageal Reflux Disease (GERD)Functional DyspepsiaChronic Gastritis, DuodenitisPeptic Ulcer of the Stomach and DuodenumDisorders of the Liver and Biliary TractChronic CholecystitisGallstone Disease (Cholelithiasis)Nonalcoholic Fatty Liver DiseaseAlcoholic Liver DiseaseLiver CirrhosisChronic PancreatitisReferencesIrritable Bowel SyndromeIntestinal DysbiosisReferences6.4. Urinary System DiseasesUrolithiasisChronic PyelonephritisChronic Kidney DiseaseCystitisReferences6.5. AnemiaIron Deficiency AnemiaB12 (Folic-) Deficiency Anemia6.6. Endocrine System DiseasesDiffuse Toxic GoiterChronic Autoimmune ThyroiditisHypothyroidismDiabetes Mellitus6.7. Rheumatic DiseasesAcute Rheumatic FeverRheumatoid ArthritisSystemic Lupus ErythematosusSystemic Sclerosis Systemic Vasculitis Dermatomyositis and PolymyositisOsteoarthritis Seronegative Spondyloarthritis6.8. Oncological DiseasesCervical CancerReferencesBreast CancerColorectal CancerProstate CancerCHAPTER 7. Organization of Work of the Out-Patient Department and Home Care7.1. Organization of the Out-Patient Department WorkThe Procedure for Admission to the Out-Patient Department General Indications and Contraindications for Treatment in Out-Patient FacilitiesRegulations on the Medical Staff of the Out-Patient Department 7.2. Organization of Home CareCHAPTER 8. Medicosocial Assessment in Internal Diseases8.1. The General Issues of Medical and Social Assessment 8.2. Medical and Social Assessment of Patients with Common Internal Diseases Chronic Obstructive Pulmonary Disease Bronchial Asthma Hypertension Myocardial Infarction Peptic Ulcer Chronic Hepatitis and Liver Cirrhosis Chronic Renal Insufficiency CHAPTER 9. Urgent Medical Aid by a General Practitioner at the Pre-Admission Stagein Case of Sudden Death 9.1. Sudden Cardiac Death 9.2. Resuscitation Measures The first stage of CPCR — Elementary Sustaining of Life The Second Stage of CPCR — Further Sustaining of Life 9.3. Prevention of Sudden Cardiac Death CHAPTER 10. Emergency Care for Pain in Family Practice 10.1. Headache 10.2. Pain in Muscular-Skeletal Conditions Lumbar Syndromes Thoracic Syndromes 10.3. Abdominal Pain 10.4. Acute Thrombosis of the Major Lower Limb Arteries 10.5. Acute Deep Vein Thrombosis of the Lower Extremities and Pelvis 10.6. Oncogenic Pain References CHAPTER 11. Diagnostics and First Aid for Syncopes, Cramps and Convulsive Syndrome11.1. Diagnostics and First Aid for Syncopes General Aspects of the Syncope Problem Non-Syncopic Conditions, which Can be Mistakenly Regarded as Fainting Cardiogenic-Mediated Syncope Syncopes in Pediatric Practice Syncopes in the Elderly Treatment of Patients with Orthostatic Hypotension Chronic Adrenal Cortex Insufficiency Neurologic and Psychiatric Variants of Loss of Consciousness Particular Situations that Can Cause a Syncope 11.2. Convulsive Syndrome, Diagnostics and Urgent Aid at the Pre-Hospital Stage Convulsive Syndrome in Children Epileptic seizures (General Information)Epileptic Seizures in Children Cramp Fasciculation Syndrome (CFS) Hyperkinesis Spasms Caused by Hysteria CHAPTER 12. Urgent Medical Aid in the Family Physician's Practical Work in Caseof Stings, Bites, Electrical Injury, Drowning, Affect of Low and High Tempera-ture 12.1. Clinical Manifestations and First Aid in Case of Stings by Hymenoptera 12.2. Snake Bites and Urgent Aid in These Cases 12.3. Clinical Manifestation and First Aid in Case of Animal Bites 12.4. Clinical Manifestation and First Aid in Case of Arthropoda Bites Black Widow (Karakurt) Bites Tarantula Bites Scorpion Stings 12.5. Clinical Manifestations and First Aid in Case of Electric Current Shock, Drown-ing,Critical Temperature Influence Electric Current Shock Drowning The Influence of Critical Temperatures
Дод.точки доступу:
Hyrina, Olha Mykolayivna
Гиріна Ольга Миколаївна
Pasiyeshvili, Liudmyla Mykhailivna
Пасієшвілі Людмила Михайлівна
Barna, Olha Mykolayivna
Барна Ольга Миколаївна
Svintsitskyi, Anatoliy Stanislavovych
Свінціцький Анатолій Станіславович
Skliarov, Ye. Ya.
Скляров Євген Якович
Biletskyi, S. V.
Білецький С. В.
Chornobrovyi, V. M.
Чорнобривий В. М.
Chukhgriyenko, N. D.
Чухрієнко Н. Д.
Babinets, L. S.
Бабінець Л. С.
Bazulevych, A. Ya. et al.
Базилевич А. Я.
Hyrina, Olha Mykolayivna \ed.\
Pasiyeshvili, Liudmyla Mykhailivna \ed.\

Примірників всього: 50
Наук.Аб. (3), ЧЗ (1), Гурт.4 (1), Уч.Аб. (45)
Вільні: Наук.Аб. (3), ЧЗ (1), Гурт.4 (1), Уч.Аб. (45)

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